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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 135 - 144 (10page)
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초록· 키워드
오류제보하기
Residual cardiovascular risk and failure of high density lipoprotein cholesterol raising treatment have refocused interest on targeting hypertriglyceridemia. Hypertriglyceridemia, triglyceride-rich lipoproteins, and remnant cholesterol have demonstrated to be important risk factors for cardiovascular disease; this has been demonstrated in experimental, genetic, and epidemiological studies. Fibrates can reduce cardiovascular event rates with or without statins. High dose omega-3 fatty acids continue to be evaluated and new specialized targeting treatment modulating triglyceride pathways, such as inhibition of apolipoprotein C-III and angiopoietin-like proteins, are being tested with regard to their effects on lipid profiles and cardiovascular outcomes. In this review, we will discuss the role of hypertriglyceridemia, triglyceride-rich lipoproteins and remnant cholesterol on cardiovascular disease, and the potential implications for treatment stargeting hypertriglyceridemia.
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등록된 정보가 없습니다.
참고문헌 (86)
참고문헌 신청
Stone NJ / 2014 / 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association task force on practice guidelines / J Am Coll Cardiol 63(25 Pt B):2889~2934
Mora S / 2012 / Determinants of residual risk in secondary prevention patients treated with high- versus low-dose statin therapy: the treating to new targets (TNT) study / Circulation 125:1979~1987
Lim S / 2013 / How to control residual cardiovascular risk despite statin treatment: Focusing on HDL–cholesterol / Int J Cardiol 166:8~14
Koh KK / 2015 / How to control residual risk during statin era? / J Am Coll Cardiol 66:1848
Mora S / 2015 / Atherogenic lipoprotein subfractions determined by ion mobility and first cardiovascular events after random allocation to high-intensity statin or placebo:the JUPITER trial / Circulation 132:2220~2229
Mora S / 2012 / Determinants of residual risk in secondary prevention patients treated with high- versus low-dose statin therapy: the treating to new targets (TNT) study / Circulation 125:1979~1987
Lim S / 2013 / How to control residual cardiovascular risk despite statin treatment: Focusing on HDL–cholesterol / Int J Cardiol 166:8~14
Koh KK / 2015 / How to control residual risk during statin era? / J Am Coll Cardiol 66:1848
Mora S / 2015 / Atherogenic lipoprotein subfractions determined by ion mobility and first cardiovascular events after random allocation to high-intensity statin or placebo:the JUPITER trial / Circulation 132:2220~2229
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