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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 4 - 10 (7page)
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초록· 키워드
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Objective: To evaluate maternal anemia and vitamin D deficiency and their associations with the neonatal hemoglobin (Hb) levels and the vitamin D status. Methods: This retrospective study enrolled a total of 120 newborns delivered at Kyungpook National University Children’s Hospital between June 2015 and June 2016. Maternal anemia was defined as an Hb level<11 g/dL and vitamin D deficiency was defined as a serum 25- hydroxyvitamin D (25-OHD) concentration<20 ng/mL. Results: The mean neonatal and maternal serum 25-OHD concentrations were 20.1±12.5 ng/mL, and 16.9±7.3 ng/mL, respectively. Sixty-eight (56.7%) of the infants and 85 (70.8%) of the mothers were vitamin D deficient. The mean maternal hemoglobin levels were 11.7±1.6 g/dL, and 38 (31.7%) of the mothers had anemia. Thirty-four (89.5%) of mothers with anemia were vitamin D deficient. After adjusting for the confounding factors, maternal vitamin D deficiency increased the risk of maternal anemia by 4.061 times (95% confidence interval [CI], 1.238–13.320; P=0.021), and neonatal vitamin D deficiency by 8.283 times (95% CI, 2.861-23.980; P<0.001) compared with maternal vitamin D non-deficiency group. One-year older maternal age decreased the risk of neonatal vitamin D deficiency (odds ratio, 0.913; 95% CI, 0.841–0.991; P=0.029). Conclusion: Maternal vitamin D deficiency increased the risk of maternal anemia and neonatal vitamin D deficiency regardless of maternal ferritin concentrations under non-inflammatory con- dition. A younger maternal age may be a risk factor for neonatal vitamin D deficiency associated with maternal anemia, and maternal vitamin D deficiency.
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참고문헌 (26)
참고문헌 신청
Choi R / 2015 / High prevalence of vitamin D deficiency in pregnant Korean women: the first trimester and the winter season as risk factors for vitamin D deficiency / Nutrients 7:3427~3448
신윤호 / 2013 / Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA) / Korean Journal of Pediatrics 56(10):439~445
박숙현 / 2015 / Severe vitamin D deficiency in preterm infants: maternal and neonatal clinical features / Korean Journal of Pediatrics 58(11):427~433
Jeong Eun Lee / 2016 / Vitamin D Status in Early Preterm Infants / Neonatal medicine 23(3):143~150
Holick MF. / 2007 / Vitamin D deficiency / N Engl J Med 357:266~281
신윤호 / 2013 / Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA) / Korean Journal of Pediatrics 56(10):439~445
박숙현 / 2015 / Severe vitamin D deficiency in preterm infants: maternal and neonatal clinical features / Korean Journal of Pediatrics 58(11):427~433
Jeong Eun Lee / 2016 / Vitamin D Status in Early Preterm Infants / Neonatal medicine 23(3):143~150
Holick MF. / 2007 / Vitamin D deficiency / N Engl J Med 357:266~281
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