지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한응급의학회 Clinical and Experimental Emergency Medicine Clinical and Experimental Emergency Medicine Vol.5 No.4
- 발행연도
- 2018.1
- 수록면
- 211 - 218 (8page)
이용수
초록· 키워드
오류제보하기
Objective This study aimed to determine whether simultaneous decreases in the serum levels of cell adhesion molecules (intracellular cell adhesion molecule-1 [ICAM-1], vascular cell adhesion molecule-1 [VCAM-1], and E-selectin) and S100 proteins within the first 24 hours after the return of spontaneous circulation were associated with good neurological outcomes in cardiac arrest survivors. Methods This retrospective observational study was based on prospectively collected data from a single emergency intensive care unit (ICU). Twenty-nine out-of-hospital cardiac arrest survivors who were admitted to the ICU for post-resuscitation care were enrolled. Blood samples were collected at 0 and 24 hours after ICU admission. According to the 6-month cerebral performance category (CPC) scale, the patients were divided into good (CPC 1 and 2, n=12) and poor (CPC 3 to 5, n=17) outcome groups. Results No difference was observed between the two groups in terms of the serum levels of ICAM-1, VCAM-1, E-selectin, and S100 at 0 and 24 hours. A simultaneous decrease in the serum levels of VCAM-1 and S100 as well as E-selectin and S100 was associated with good neurological outcomes. When other variables were adjusted, a simultaneous decrease in the serum levels of VCAM-1 and S100 was independently associated with good neurological outcomes (odds ratio, 9.285; 95% confidence interval, 1.073 to 80.318; P=0.043). Conclusion A simultaneous decrease in the serum levels of soluble VCAM-1 and S100 within the first 24 hours after the return of spontaneous circulation was associated with a good neurological outcome in out-of-hospital cardiac arrest survivors.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Fink K / 2015 / Selenium prevents microparticle-induced endothelial inflammation in patients after cardiopulmonary resuscitation / Crit Care 19:58
Ahn KO / 2010 / Epidemiology and outcomes from non-traumatic out-of-hospital cardiac arrest in Korea: a nationwide observational study / Resuscitation 81:974~981
Nolan JP / 2008 / Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke / Resuscitation 79:350~379
Ballabh P / 2004 / The blood-brain barrier: an overview. Structure, regulation, and clinical implications / Neurobiol Dis 16:1~13
Lucas SM / 2006 / The role of inflammation in CNS injury and disease / Br J Pharmacol 147(Suppl 1):S232~S240
Ahn KO / 2010 / Epidemiology and outcomes from non-traumatic out-of-hospital cardiac arrest in Korea: a nationwide observational study / Resuscitation 81:974~981
Nolan JP / 2008 / Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke / Resuscitation 79:350~379
Ballabh P / 2004 / The blood-brain barrier: an overview. Structure, regulation, and clinical implications / Neurobiol Dis 16:1~13
Lucas SM / 2006 / The role of inflammation in CNS injury and disease / Br J Pharmacol 147(Suppl 1):S232~S240
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
병원 밖에서 발생한 심인성 심장정지환자의 신경학적 결과 관련 요인 - 7년간 국가심장정지조사사업 자료 활용 -
대한응급의학회지
2016 .01
-
APACHE II Score Immediately after Cardiac Arrest as a Predictor of Good Neurological Outcome in Out-of-Hospital Cardiac Arrest Patients Receiving Targeted Temperature Management
Acute and Critical Care
2018 .01
-
Spatiotemporal Analysis of Out-of-Hospital Cardiac Arrest Incidence and Survival Outcomes in Korea (2009–2021)
Journal of Korean Medical Science
2024 .03
-
Brain Magnetic Resonance Imaging in Patients with Favorable Outcomes after Out-of-Hospital Cardiac Arrest: Many Have Encephalopathy Even with a Good Cerebral Performance Category Score
Acute and Critical Care
2015 .01
-
Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest and in-hospital cardiac arrest with return of spontaneous circulation: be careful when comparing apples to oranges
Acute and Critical Care
2023 .05
-
Main outcomes of the Sudden cardiac arrest survey 2006 to 2016
Clinical and Experimental Emergency Medicine
2019 .01
-
Application of a Dual-Dispatch System for Out-of-Hospital Cardiac Arrest Patients: Will More Hands Save More Lives?
Journal of Korean Medical Science
2019 .01
-
Association between the D-dimer to fibrinogen ratio and neurological outcomes in patients with witnessed out-of-hospital cardiac arrest treated with targeted temperature management
대한응급의학회지
2024 .08
-
Selectins: functional importance as cell adhesion molecule in immune system
Journal of Biomedical and Translational Research
2019 .01
-
Risk factors for hospital mortality in intensive care unit survivors: a retrospective cohort study
Acute and Critical Care
2023 .02
-
심정지 여부에 따른 목맴 환자의 특징과 예후인자로서의 S100B 단백질의 유용성
대한응급의학회지
2015 .01
-
Effect of National Implementation of Telephone CPR Program to Improve Outcomes from Out-of-Hospital Cardiac Arrest: an Interrupted Time-Series Analysis
Journal of Korean Medical Science
2018 .01
-
Association between a Multidisciplinary Team Approach and Clinical Outcomes in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation in the Emergency Department
Korean Circulation Journal
2021 .11
-
Prognostic factors related with outcomes in out-of-hospital cardiac arrest due to pesticide poisoning in South Korea: a nationwide population-based study
대한응급의학회지
2024 .02
-
Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest
Acute and Critical Care
2016 .01
-
Management of post-cardiac arrest syndrome
Acute and Critical Care
2019 .01
-
병원 밖에서 발생한 급성 심장정지 환자의 생존결과에 영향을 미치는 요인 : 다수준 분석
한국응급구조학회지
2020 .01
-
2020 Korean Guidelines for Cardiopulmonary Resuscitation. Part 5. Post-Cardiac Arrest Care
Clinical and Experimental Emergency Medicine
2021 .05
-
2020 Korean Guidelines for Cardiopulmonary Resuscitation. Part 5. Post-Cardiac Arrest Care
Clinical and Experimental Emergency Medicine
2021 .01
-
Recent Update in Out-of-Hospital Cardiac Arrests in Korea
Korean Circulation Journal
2021 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0