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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 737 - 742 (6page)
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초록· 키워드
오류제보하기
History of treatment for tuberculosis (TB) is a risk factor for obstructive lung disease. However, it has been unclear whether the clinical characteristics of patients with destroyed lung by TB differ according to the presence or absence of airflow limitation. The objective of the study was to evaluate differences in acute exacerbations and forced expiratory volume in 1 second (FEV1) decline in patients with destroyed lung by TB according to the presence or absence of airflow limitation. We performed a retrospective cohort study and enrolled patients with destroyed lung by TB. The presence of airflow limitation was defined as FEV1/forced vital capacity (FVC) < 0.7. One hundred and fifty-nine patients were enrolled, and 128 (80.5%) had airflow limitation. The proportion of patients who experienced acute exacerbation was higher in patients with airflow limitation compared to those without (89.1 vs. 67.7%, respectively; P = 0.009). The rate of acute exacerbation was higher in patients with airflow limitation (IRR, 1.19; 95% CI, 1.11-1.27). Low body mass index (X vs. X + 1; HR, 0.944; 95% CI, 0.895-0.996) in addition to airflow limitation (HR, 1.634; 95% CI, 1.012-2.638), was an independent risk factor for acute exacerbation. The annual decline of FEV1 was 2 mL in patients with airflow limitation and 36 mL in those without (P < 0.001). In conclusion, the presence of airflow limitation is an independent risk factor for acute exacerbation in patients with the destroyed lung by TB.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Corbett EL / 2003 / The growing burden of tuberculosis : global trends and interactions with the HIV epidemic / Arch Intern Med 163:1009~1021
Pasipanodya JG / 2007 / Pulmonary impairment after tuberculosis / Chest 131:1817~1824
Plit ML / 1998 / Influence of antimicrobial chemotherapy on spirometric parameters and pro-inflammatory indices in severe pulmonary tuberculosis / Eur Respir J 12:351~356
채진녕 / 2011 / 결핵성 파괴폐의 흉부 전산화단층촬영 소견 및 폐기능과의 상관관계 / Tuberculosis and Respiratory Diseases 71(3):202~209
Hnizdo E / 2000 / Chronic pulmonary function impairment caused by initial and recurrent pulmonary tuberculosis following treatment / Thorax 55:32~38
Pasipanodya JG / 2007 / Pulmonary impairment after tuberculosis / Chest 131:1817~1824
Plit ML / 1998 / Influence of antimicrobial chemotherapy on spirometric parameters and pro-inflammatory indices in severe pulmonary tuberculosis / Eur Respir J 12:351~356
채진녕 / 2011 / 결핵성 파괴폐의 흉부 전산화단층촬영 소견 및 폐기능과의 상관관계 / Tuberculosis and Respiratory Diseases 71(3):202~209
Hnizdo E / 2000 / Chronic pulmonary function impairment caused by initial and recurrent pulmonary tuberculosis following treatment / Thorax 55:32~38
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