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대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.68 No.1
발행연도
2015.1
수록면
3 - 12 (10page)

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Pain is a predictable consequence following operations, but the management of postoperative pain is another challengefor anesthesiologists and inappropriately controlled pain may lead to unwanted outcomes in the postoperative period. Opioids are indeed still at the mainstream of postoperative pain control, but solely using only opioids for postoperativepain management may be connected with risks of complications and adverse effects. As a consequence, the concept ofmultimodal analgesia has been proposed and is recommended whenever possible. Acetaminophen is one of the mostcommonly used analgesic and antipyretic drug for its good tolerance and high safety profiles. The introduction of intravenousform of acetaminophen has led to a wider flexibility of its use during peri- and postoperative periods, allowingthe early initiation of multimodal analgesia. Many studies have revealed the efficacy, safety and opioid sparing effectsof intravenous acetaminophen. Intravenous ibuprofen has also shown to be well tolerated and demonstrated to havesignificant opioid sparing effects during the postoperative period. However, the number of randomized controlled trialsconfirming the efficacy and safety is small and should be used in caution in certain group of patients. Intravenousacetaminophen and ibuprofen are important options for multimodal postoperative analgesia, improving pain and patientsatisfaction.

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