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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 98 - 108 (11page)
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초록· 키워드
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Purpose: The aim of this study was to validate a computational fluid dynamics (CFD) simulationof flow-diverter treatment through Doppler ultrasonography measurements in patient-specificmodels of intracranial bifurcation and side-wall aneurysms.
Methods: Computational and physical models of patient-specific bifurcation and sidewallaneurysms were constructed from computed tomography angiography with use ofstereolithography, a three-dimensional printing technology. Flow dynamics parametersbefore and after flow-diverter treatment were measured with pulse-wave and color Dopplerultrasonography, and then compared with CFD simulations.
Results: CFD simulations showed drastic flow reduction after flow-diverter treatment in bothaneurysms. The mean volume flow rate decreased by 90% and 85% for the bifurcation aneurysmand the side-wall aneurysm, respectively. Velocity contour plots from computer simulationsbefore and after flow diversion closely resembled the patterns obtained by color Dopplerultrasonography.
Conclusion: The CFD estimation of flow reduction in aneurysms treated with a flow-divertingstent was verified by Doppler ultrasonography in patient-specific phantom models of bifurcationand side-wall aneurysms. The combination of CFD and ultrasonography may constitute a feasibleand reliable technique in studying the treatment of intracranial aneurysms with flow-diverting stents.
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등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Yu SC / 2012 / Intracranial aneurysms: midterm outcome of pipeline embolization device: a prospective study in 143 patients with 178 aneurysms / Radiology 265:893~901
Brinjikji W / 2013 / Endovascular treatment of intracranial aneurysms with flow diverters: a meta-analysis / Stroke 44:442~447
Chong W / 2014 / Computational hemodynamics analysis of intracranial aneurysms treated with flow diverters: correlation with clinical outcomes / AJNR Am J Neuroradiol 35:136~142
Cebral JR / 2011 / Aneurysm rupture following treatment with flow-diverting stents:computational hemodynamics analysis of treatment / AJNR Am J Neuroradiol 32:27~33
Shojima M / 2004 / Magnitude and role of wall shear stress on cerebral aneurysm:computational fluid dynamic study of 20 middle cerebral artery aneurysms / Stroke 35:2500~2505
Brinjikji W / 2013 / Endovascular treatment of intracranial aneurysms with flow diverters: a meta-analysis / Stroke 44:442~447
Chong W / 2014 / Computational hemodynamics analysis of intracranial aneurysms treated with flow diverters: correlation with clinical outcomes / AJNR Am J Neuroradiol 35:136~142
Cebral JR / 2011 / Aneurysm rupture following treatment with flow-diverting stents:computational hemodynamics analysis of treatment / AJNR Am J Neuroradiol 32:27~33
Shojima M / 2004 / Magnitude and role of wall shear stress on cerebral aneurysm:computational fluid dynamic study of 20 middle cerebral artery aneurysms / Stroke 35:2500~2505
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