지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objective：The aim of this study is to compare cortical thickness in late life major depression patients without cerebral vascular disease (CVD) with that of non-depressed normal comparison subjects using magnetic resonance imaging (MRI). Methods：Altogether, 47 subjects were finally recruited from the Memory impairment clinics of Pusan National University Hospital in Korea. All subjects (late life major depression patients without CVD : n=21, matched non-depressed normal comparison subjects : n=26) underwent 3-tesla MRI. Results：Late life major depression patients without CVD showed reduced cortical thickness in left precuneus, left inferior temporal gyrus, and left cuneus compared with non-depressed normal comparison subjects. Conclusion：Our findings suggest that late life major depression without CVD is associated with reduced cortical thickness.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
O’Brien JT / 2004 / A longitudinal study of hippocampal volume, cortisol levels, and cognition in older depressed subjects / Am J Psychiatry 161:2081~2090
Sheline YI / 2006 / Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed / Biol Psychiatry 60:58~65
Alexopoulos GS / 2005 / Depression in the elderly / Lancet 365:1961~1970
Crocco EA / 2010 / How late-life depression affects cognition : neural mechanisms / Curr Psychiatry Rep 12:34~38
Alexopoulos GS / 1997 / ‘Vascular depression’ hypothesis / Arch Gen Psychiatry 54:915~922
Sheline YI / 2006 / Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed / Biol Psychiatry 60:58~65
Alexopoulos GS / 2005 / Depression in the elderly / Lancet 365:1961~1970
Crocco EA / 2010 / How late-life depression affects cognition : neural mechanisms / Curr Psychiatry Rep 12:34~38
Alexopoulos GS / 1997 / ‘Vascular depression’ hypothesis / Arch Gen Psychiatry 54:915~922
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