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논문 기본 정보

자료유형
학술저널
저자정보
Jae Woo An (Chungbuk National University) Sung Bo Cho (Inner Mongolia University for Nationalities) Ji Hwan Lee (Chungbuk National University) Han Jin Oh (Chungbuk National University) Yong Ju Kim (Chungbuk National University) Se Yeon Chang (Chungbuk National University) Young Bin Go (Chungbuk National University) Dong Cheol Song (Chungbuk National University) Hyun Ah Cho (Chungbuk National University) Jin Ho Cho (Chungbuk National University)
저널정보
충남대학교 농업과학연구소 Korean Journal of Agricultural Science Korean Journal of Agricultural Science Vol.49 No.3
발행연도
2022.9
수록면
389 - 396 (8page)

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The purpose of this study was to investigate the safety of Houttuynia cordata Thunb extract (HCE) in Institute of Cancer Research (ICR) mice, to determine the effects of the extract on the growth performance and colony count, and to establish the optimal concentration of HCE. In total, 60 fiveweek-old male ICR mice with an average initial body weight (BW) of 27.24 ± 0.44 g were used in a fourweek experiment. Mice were randomly allotted to four treatment groups (five replications per group, three mice per cage): 1) a control (CON) group fed with normal distilled water; 2) treatment group 1 (T1) fed with normal distilled water containing 0.05% HCE; 3) treatment group 3 (T3) fed with normal distilled water containing 0.1% HCE; and 4) treatment group 3 (T3) fed with normal distilled water containing 0.2% HCE. BW, feed intake (FI), and water intake were measured on the first, fourteenth, and eighteenth days. T2 showed a significant improvement (p < 0.05) in the feed conversion ratio (FCR) over the experimental period. However, water intake levels did not show significant differences among the groups. In the large intestine and feces, E. coli and Lactobacillus levels were significantly improved (p < 0.05) in the HCE treated group compared to the CON group. Supplying HCE via the drinking water improved the growth performance and colony count in ICR mice. Based on results of this study, utilizing HCE in livestock species is expected to be safe and feasible.

목차

Abstract
Introduction
Materials and Method
Result and Discussion
Conclusion
References

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