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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.1
- 수록면
- 63 - 68 (6page)
- DOI
- 10.4082/kjfm.21.0102
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초록· 키워드
오류제보하기
Background: The association between serum cholesterol levels and depression has been studied extensively; how-ever, results are inconsistent. This study aimed to investigate the association between low-density lipoprotein cho-lesterol (LDL-C) levels and depressive symptoms among Korean adults.Methods: This cross-sectional study used data obtained from the 2007?2015 Korea National Health and Nutrition Examination Survey. In total, 40,904 adults were included in the final analysis. Participants were categorized into five groups according to their LDL-C levels, using the Korean guidelines for dyslipidemia. Symptoms of depression were evaluated using a self-reported questionnaire. Weighted logistic regression was used to examine the relation-ship between LDL-C levels and self-reported depressive symptoms.Results: Compared with the intermediate category, the lowest (<70 mg/dL) and highest (≥160 mg/dL) LDL-C cate-gories were associated with depressive symptoms, after adjusting for potential confounding factors (odds ratio [OR], 1.191; 95% confidence interval [CI], 1.008?1.409; OR, 1.241; 95% CI, 1.073?1.435, respectively). The highest LDL-C category was positively associated with depressive symptoms in those who were middle-aged, female, had a low body mass index, and taking or not taking dyslipidemia medications.Conclusion: A U-shaped association was identified between LDL-C categories and self-reported depressive symp-toms. Our findings suggest that LDL-C levels that are too low or too high are associated with self-reported depres-sive symptoms. Further prospective studies are needed to determine the causal relationship of this association.
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