지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.1
- 수록면
- 37 - 46 (10page)
- DOI
- 10.12997/jla.2023.12.1.37
이용수
초록· 키워드
오류제보하기
Dyslipidemia is an important risk factor for atherosclerotic cardiovascular disease (ASCVD). There are abundant and unequivocal data to indicate that low-density lipoproteins (LDL) are a cause of ASCVD. Reduction of plasma low-density lipoprotein cholesterol (LDL-C) by medical therapy such as statins, ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have proven to significantly reduce the risk of cardiovascular events. However, for many reasons, many patients are not able to achieve LDL-C levels recommended by guidelines on currently available therapies. This has led to the development of new drugs lowering LDL-C, such as inclisiran, bempedoic acid, and evinacumab, in the hope of reducing cardiovascular (CV) risk. Drugs targeting lipoprotein (a) (Lp[a]) also have a role in the prevention of atherosclerosis, with genetic studies having established that 20%–30% of the human population inherits plasma Lp(a) levels in the atherogenic range. In this paper, we will review the recent progress made in the approaches to LDL-C and Lp(a) therapeutic modulation.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Pharmacological Strategies beyond Statins: Ezetimibe and PCSK9 Inhibitors
지질·동맥경화학회지
2019 .01
-
Recent Updates of Lipoprotein(a) and Cardiovascular Disease
전남의대학술지
2021 .01
-
Non-achievement of the Low-Density Lipoprotein Cholesterol Goal in Older Patients with Type 2 Diabetes Mellitus and a Very High Cardiovascular Disease Risk: A Multicenter Study in Vietnam
Annals of geriatric medicine and research
2021 .12
-
Current drugs, targets, and drug delivery systems for the treatment of dyslipidemia
Journal of Pharmaceutical Investigation
2018 .05
-
Intuitive Modification of the Friedewald Formula for Calculation of LDL-Cholesterol
Annals of Laboratory Medicine
2023 .01
-
New Drugs for Treating Dyslipidemia: Beyond Statins
Diabetes and Metabolism Journal
2015 .01
-
Association between Low-Density Lipoprotein Cholesterol Level and Cardiovascular Outcomes in Korean Adults: A Nationwide Cohort Study
Diabetes and Metabolism Journal
2023 .01
-
Myocardial Infarction, Stroke, and All-Cause Mortality according to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study
Diabetes and Metabolism Journal
2022 .09
-
고지혈증 치료 가이드라인
대한내과학회지
2019 .10
-
The Potential Role of Biomarkers Associated with ASCVD Risk: Risk-Enhancing Biomarkers
지질·동맥경화학회지
2019 .01
-
Lipid Management in Korean People with Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
Diabetes and Metabolism Journal
2023 .01
-
Lipid Management in Korean People With Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
지질·동맥경화학회지
2023 .01
-
Mechanism, clinical consequences, and management of dyslipidemia in children with nephrotic syndrome
Childhood Kidney Diseases
2022 .06
-
Serum Low-Density Lipoprotein Cholesterol Levels and Depressive Mood in Korean Adults: A Nationwide Population-Based Study
Korean Journal of Family Medicine
2022 .01
-
Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments
Endocrinology and Metabolism
2020 .01
-
Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia
Endocrinology and Metabolism
2021 .01
-
The Effects of Anti-thyroid Drugs on Lipoproteins and Insulin Resistance in Graves’ Disease: A Randomized Clinical Trial
지질·동맥경화학회지
2024 .09
-
Direct LDL Cholesterol Assay vs. Estimated Equations in Patients With Hypertriglyceridemia or Low LDL Cholesterol Levels
Annals of Laboratory Medicine
2024 .07
-
Risk of Cardiovascular Disease according to Baseline Low-Density Lipoprotein Cholesterol Level in Different Age Groups in Korean Diabetes Population: A Cohort Study
Diabetes and Metabolism Journal
2024 .03
-
Inference of a causal relation between low-density lipoprotein cholesterol and hypertension using mendelian randomization analysis
Clinical Hypertension
2021 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0