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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 367 - 376 (10page)
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Background: This study assessed the proportion of risk-stratified Korean patients with dyslipidemia achieving their low-density lipoprotein cholesterol (LDL-C) targets as defined by the European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) (2011) guidelines while receiving lipid-modifying treatments (LMTs). Methods: In this multicenter, cross-sectional, observational study, we evaluated data from Korean patients aged ≥19 years whowere receiving LMTs for ≥3 months and had an LDL-C value within the previous 12 months on the same LMT. Data were collectedfor demographics, cardiovascular (CV) risk factors, medical history, and healthcare consumption. Patients were risk-stratified according to the ESC Systematic COronary Risk Evaluation (SCORE) chart and LDL-C target achievement rate was assessed. Results: Guideline-based risk-stratification of the 1,034 patients showed the majority (72.2%) to be in the very high-risk category. Investigators’ assessment of risk was underestimated in 71.6% compared to ESC/EAS guidelines. Overall LDL-C target achievement rate was 44.3%; target achievement was the highest (66.0%) in moderate-risk patients and the lowest (39.0%) in very high-riskpatients. Overall 97.1% patients were receiving statin therapy, mostly as a single-agent (89.2%). High-intensity statins and the highest permissible dose of high-intensity statins had been prescribed to only 9.1% and 7.3% patients in the very high-risk group, respectively. Physician satisfaction with patients’ LDL-C levels was the primary reason for non-intensification of statin therapy. Conclusion: Achievement of target LDL-C level is suboptimal in Korean patients with dyslipidemia, especially in those at veryhigh-risk of CV events. Current practices in LMTs need to be improved based on precise CV risk evaluation posed by dyslipidemia.
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참고문헌 (36)
참고문헌 신청
김명희 / 2004 / Prevalence of the Metabolic Syndrome and Its Association with Cardiovascular Diseases in Korea / Journal of Korean Medical Science 19(2):195~201
Jung KH / 2012 / Secular trends in ischemic stroke characteristics in a rapidly developed country : results from the Korean Stroke Registry Study(secular trends in Korean stroke) / Circ Cardiovasc Qual Outcomes 5:327~334
신현영 / 2016 / 2014년 사망원인 통계 / 대한의사협회지 59(3):221~232
노은 / 2013 / Prevalence and Management of Dyslipidemia in Korea:Korea National Health and Nutrition Examination Survey during 1998 to 2010 / Diabetes and Metabolism Journal 37(6):433~449
Wilson PW / 1998 / Prediction of coronary heart disease using risk factor categories / Circulation 97:1837~1847
Jung KH / 2012 / Secular trends in ischemic stroke characteristics in a rapidly developed country : results from the Korean Stroke Registry Study(secular trends in Korean stroke) / Circ Cardiovasc Qual Outcomes 5:327~334
신현영 / 2016 / 2014년 사망원인 통계 / 대한의사협회지 59(3):221~232
노은 / 2013 / Prevalence and Management of Dyslipidemia in Korea:Korea National Health and Nutrition Examination Survey during 1998 to 2010 / Diabetes and Metabolism Journal 37(6):433~449
Wilson PW / 1998 / Prediction of coronary heart disease using risk factor categories / Circulation 97:1837~1847
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