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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.2
- 수록면
- 90 - 99 (10page)
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초록· 키워드
오류제보하기
Caenorhabditis elegans is an important model organism with many useful features, including rapid development and aging, easy cultivation, and genetic tractability. Survival assays using C. elegans are powerful methods for studying physiological processes. In this review, we describe diverse types of C. elegans survival assays and discuss the aims, uses, and ad-vantages of specific assays. C. elegans survival assays have played key roles in identifying novel genetic factors that regulate many aspects of animal physiology, such as aging and lifespan, stress response, and immunity against pathogens. Because many genetic factors discovered using C. elegans are evolutionarily conserved, survival assays can provide insights into mechanisms underlying physiological processes in mammals, including humans.
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등록된 정보가 없습니다.
참고문헌 (87)
참고문헌 신청
Aitlhadj, L. / 2010 / The use of FUdR can cause prolonged longevity in mutant nematodes / Mech. Ageing Dev 131:364~365
Alspaugh, J. A. / 2015 / Virulence mechanisms and Cryptococcus neoformans pathogenesis / Fungal Genet. Biol 78:55~58
Ozlem Altintas / 2016 / The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster / BMB Reports 49(2):81~92
Amrit, F. R. / 2014 / The C. elegans lifespan assay toolkit / Methods 68:465~475
Barsyte, D. / 2001 / Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans / FASEB J 15:627~634
Alspaugh, J. A. / 2015 / Virulence mechanisms and Cryptococcus neoformans pathogenesis / Fungal Genet. Biol 78:55~58
Ozlem Altintas / 2016 / The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster / BMB Reports 49(2):81~92
Amrit, F. R. / 2014 / The C. elegans lifespan assay toolkit / Methods 68:465~475
Barsyte, D. / 2001 / Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans / FASEB J 15:627~634
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