지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 464 - 470 (7page)
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초록· 키워드
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Background: Prediabetes is a metabolic state between normoglycemia and diabetes and is known to carry a higher risk of developing overt diabetes and cardiovascular disease (CVD). The relative and absolute risks of all-cause mortality, CVD, coronary heart disease, and stroke in prediabetes patients, as well as in diabetic patients, is higher than that in patients with normoglycemia. Carotid intima-media thickness (cIMT) is a method used to stratify CVD risk. In this study, we aimed to determine whether the neutrophil-to-lymphocyte ratio (NLR) correlates with cIMT in prediabetes patients.Methods: From January 1, 2016, to February 20, 2021, 581 adults their 30s?70s who underwent carotid ultrasonog-raphy as part of a comprehensive medical examination at the Dongtan Sacred Heart Hospital were enrolled. Statis-tical analysis using SPSS presented t-test and chi-square test significance levels into a group with normal cIMT (nIMT; cIMT <1 mm) and a group with thick cIMT (tIMT; cIMT ≥1 mm). Binary logistic regression analysis was performed to confirm the correlation between NLR and cIMT.Results: In prediabetic adults, age, hemoglobin A1c (HbA1c), systolic blood pressure, and NLR were significantly higher in the tIMT group than in the nIMT group. In the regression analysis, NLR, age, and HbA1c were significantly correlated with cIMT.Conclusion: NLR was significantly higher in the tIMT group than in the nIMT group; therefore, NLR may be used to assess CVD risk in prediabetes patients.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Chan-Hee Jung / 2021 / Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status / Diabetes & Metabolism Journal 45(1):1~10
Brannick B / 2018 / Prediabetes and cardiovascular disease : pathophysiology and interventions for prevention and risk reduction / Endocrinol Metab Clin North Am 47:33~50
Piepoli MF / 2016 / 2016 European Guidelines on cardiovascular disease prevention in clinical practice: the sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR) / Eur Heart J 37(2016):2315~2381
Mathers CD / 2009 / Global and regional causes of death / Br Med Bull 92:7~32
Burke GL / 1995 / Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults : the Atherosclerosis Risk in Communities(ARIC)Study / Stroke 26:386~391
Brannick B / 2018 / Prediabetes and cardiovascular disease : pathophysiology and interventions for prevention and risk reduction / Endocrinol Metab Clin North Am 47:33~50
Piepoli MF / 2016 / 2016 European Guidelines on cardiovascular disease prevention in clinical practice: the sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR) / Eur Heart J 37(2016):2315~2381
Mathers CD / 2009 / Global and regional causes of death / Br Med Bull 92:7~32
Burke GL / 1995 / Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults : the Atherosclerosis Risk in Communities(ARIC)Study / Stroke 26:386~391
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