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논문 기본 정보

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학술저널
저자정보
Eman Ali (Department of Anesthesiology and Reanimation Sakarya Training and Research Hospital Sakarya Turkey.) Balaban Onur (Department of Anesthesiology and Reanimation Sakarya University Faculty of Medicine Training and Re) Kocayiğit Havva (Department of Anesthesiology and Reanimation Sakarya Training and Research Hospital Sakarya Turkey.) Süner Kezban Özmen (Department of Intensive Care Sakarya Training and Research Hospital Sakarya Turkey.) Cırdı Yaşar (Department of Intensive Care Sakarya Training and Research Hospital Sakarya Turkey.) Erdem Ali Fuat (Department of Anesthesiology and Reanimation Sakarya University Faculty of Medicine Training and Re)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.44
발행연도
2021.11
수록면
1 - 10 (10page)
DOI
10.3346/jkms.2021.36.e309

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Background: We assessed maternal and neonatal outcomes of critically ill pregnant and puerperal patients in the clinical course of coronavirus disease 2019 (COVID-19). Methods: Records of pregnant and puerperal women with polymerase chain reaction positive COVID-19 virus who were admitted to our intensive care unit (ICU) from March 2020 to August 2021 were investigated. Demographic, clinical and laboratory data, pharmacotherapy, and neonatal outcomes were analyzed. These outcomes were compared between patients that were discharged from ICU and patients who died in ICU. Results: Nineteen women were included in this study. Additional oxygen was required in all cases (100%). Eight patients (42%) were intubated and mechanically ventilated. All patients that were mechanically ventilated have died. Increased levels of C-reactive protein (CRP) was seen in all patients (100%). D-dimer values increased in 15 patients (78.9%); interleukin-6 (IL-6) increased in 16 cases (84.2%). Sixteen patients used antiviral drugs. Eleven patients were discharged from the ICU and eight patients have died due to complications of COVID-19 showing an ICU mortality rate of 42.1%. Mean number of hospitalized days in ICU was significantly lower in patients that were discharged (P = 0.037). Seventeen patients underwent cesarean-section (C/S) (89.4%). Mean birth week was significantly lower in patients who died in ICU (P = 0.024). Eleven preterm (57.8%) and eight term deliveries (42.1%) occurred. Conclusion: High mortality rate was detected among critically ill pregnant/parturient patients followed in the ICU. Main predictors of mortality were the need of invasive mechanical ventilation and higher number of days hospitalized in ICU. Rate of C/S operations and preterm delivery were high. Pleasingly, the rate of neonatal death was low and no neonatal COVID-19 occurred.
#SARS-CoV-2 #COVID-19 #Critical Ill #Pregnancy #Puerperium #Clinical Outcome

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참고문헌 (26)

참고문헌 신청
Søreide K / 2020 / Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services / Br J Surg 107(10):1250~1261 google schola Huntley BJ / 2020 / Rates of maternal and perinatal mortality and vertical transmission in pregnancies complicated by severe acute respiratory syndrome coronavirus 2(SARS-Co-V-2)infection : a systematic review / Obstet Gynecol 136(2):303~312 google schola Allotey J / 2020 / Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis / BMJ 370:m3320 google schola Vallejo V / 2020 / A postpartum death due to coronavirus disease 2019(COVID-19)in the United States / Obstet Gynecol 136(1):52~55 google schola Blauvelt CA / 2020 / Acute respiratory distress syndrome in a preterm pregnant patient with coronavirus disease 2019(COVID-19) / Obstet Gynecol 136(1):46~51 google schola

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