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논문 기본 정보

자료유형
학술저널
저자정보
Zeeshan Sheikh (University of Toronto Canada) Nader Hamdan (Dalhousie University) Yuichi Ikeda (University of Toronto Canada) Marc Grynpas (Mt. Sinai Hospital) Bernhard Ganss (University of Toronto) Michael Glogauer (University of Toronto Canada)
저널정보
한국생체재료학회 생체재료학회지 생체재료학회지 제21권 제2호
발행연도
2017.6
수록면
17 - 36 (20page)
DOI
10.1186/s40824-017-0095-5

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Periodontal disease is categorized by the destruction of periodontal tissues. Over the years, there have been several clinical techniques and material options that been investigated for periodontal defect repair/regeneration. The development of improved biomaterials for periodontal tissue engineering has significantly improved the available treatment options and their clinical results. Bone replacement graft materials, barrier membranes, various growth factors and combination of these have been used. The available bone tissue replacement materials commonly used include autografts, allografts, xenografts and alloplasts. These graft materials mostly function as osteogenic, osteoinductive and/or osteoconductive scaffolds. Polymers (natural and synthetic) are more widely used as a barrier material in guided tissue regeneration (GTR) and guided bone regeneration (GBR) applications. They work on the principle of epithelial cell exclusion to allow periodontal ligament and alveolar bone cells to repopulate the defect before the normally faster epithelial cells. However, in an attempt to overcome complications related to the epithelial down-growth and/or collapse of the non-rigid barrier membrane and to maintain space, clinicians commonly use a combination of membranes with hard tissue grafts. This article aims to review various available natural tissues and biomaterial based bone replacement graft and membrane options used in periodontal regeneration applications.

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