지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.6
- 수록면
- 302 - 306 (5page)
이용수
초록· 키워드
오류제보하기
Background: The Koebner phenomenon (KP) is a common entity observed in dermatological disorders. The reported incidence of KP in vitiligo varies widely. Although the KP is frequently observed in patients with viltiligo, the associated factors with KP has not been established yet. Objective: The aim is to estimate the prevalence of KP in vitiligo patients and to investigate the associated factors with KP among vitiligo characteristics.
Methods: A cross-sectional observational study was conducted using 381 vitiligo patients. Demographic and clinical information was obtained via the completion of Vitiligo European Task Force (VETF) questionnaires. Patients with positive history of KP were extracted from this vitiligo database. Multivariate analysis was performed to assess associations with KP. Results: The median age of cases was 24 years (range, 0.6∼76). In total, 237 of the patients were male (62.2%). Vitiligo vulgaris was the most common type observed (152/381, 39.9%). Seventy-two percent (274/381) patients did not exhibit KP, whereas 28.1% (107/381) of patients exhibited this condition. Multivariable analysis showed the following to be independent factors with KP in patients with vitiligo: the progressive disease (odds ratio [OR], 1.82; 95% confidence interval [95% CI], 1.17∼2.92; p=0.041), disease duration longer than 5 years (OR, 1.92; 95% CI, 1.22∼2.11; p=0.003), and body surface area more than 2% (OR, 2.20; 95% CI, 1.26∼3.24; p＜0.001). Conclusion: Our results suggest that KP may be used to evaluate disease activity and investigate different associations between the clinical profile and course of vitiligo. Further studies are needed to predict the relationship between KP and responsiveness to therapy.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Gawkrodger DJ / 2010 / Vitiligo: concise evidence based guidelines on diagnosis and management / Postgrad Med J 86:466~471
Morais P / 2013 / Striae: a potential precipitating factor for Koebner phenomenon in psoriasis? / Dermatol Online J 19:18186
van Geel N / 2011 / Koebner's phenomenon in vitiligo:European position paper / Pigment Cell Melanoma Res 24:564~573
Barona MI / 1995 / An epidemiologic case-control study in a population with vitiligo / J Am Acad Dermatol 33:621~625
Taïeb A / 2007 / The definition and assessment of vitiligo: a consensus report of the vitiligo European task force / Pigment Cell Res 20:27~35
Morais P / 2013 / Striae: a potential precipitating factor for Koebner phenomenon in psoriasis? / Dermatol Online J 19:18186
van Geel N / 2011 / Koebner's phenomenon in vitiligo:European position paper / Pigment Cell Melanoma Res 24:564~573
Barona MI / 1995 / An epidemiologic case-control study in a population with vitiligo / J Am Acad Dermatol 33:621~625
Taïeb A / 2007 / The definition and assessment of vitiligo: a consensus report of the vitiligo European task force / Pigment Cell Res 20:27~35
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