지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 86 - 93 (8page)
- DOI
- 10.16956/jes.2021.21.4.86
이용수
초록· 키워드
오류제보하기
Purpose: The study was designed to determine the long-term outcome of the blood pressure after surgical treatment in primary hyperaldosteronism.
Methods: The medical records of patients with unilateral primary hyperaldosteronism who had undergone laparoscopic adrenalectomy were retrospectively reviewed from January 2001 to December 2020 in a single center. Patient demographics, postoperative blood pressure changes and related factors of clinical success in patients with primary hyperaldosteronism were analyzed.
Results: Of 63 patients enrolled and analyzed, 32 (51%) achieved complete clinical success, 31 (49%) achieved partial clinical success, and 0 (0%) had no clear success. However, within the partial clinical success group, the mean±standard deviation systolic and diastolic BP decreased significantly by 23.3±28.5 mmHg (P<0.01) and 6.5±18.9 mmHg (P=0.06), respectively. Also, the number of antihypertensive medications used decreased from 6 (range, 3?16) to 2 (range, 0.5?6.5) (P<0.01). In univariate analysis, being male (P<0.01), the number of preoperative anti-hypertensive drugs administered (P<0.01), and the preoperative systolic blood pressure (P=0.01) were the main factors related to partial clinical success after adrenalectomy. In multivariate regression analysis, uncured hypertension was independently associated with the number of preoperative antihypertensive agents (P=0.04) Conclusion: Although hypertension cannot be cured in all patients, unilateral adrenalectomy performed for localized primary hyperaldosteronism is effective in improving hypertension in patients with primary hyperaldosteronism.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Conn JW / 1955 / Presidential address. I. Painting background. II. Primary aldosteronism, a new clinical syndrome / J Lab Clin Med 45:3~17
Plouin PF / 2004 / Trends in the prevalence of primary aldosteronism, aldosteroneproducing adenomas, and surgically correctable aldosterone-dependent hypertension / Nephrol Dial Transplant 19:774~777
Giacchetti G / 2006 / Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronism : need for a standardized protocol / J Hypertens 24:737~745
Campagnacci R / 2009 / Long-term results of laparoscopic adrenalectomy for primary aldosteronism / J Endocrinol Invest 32:57~62
Sukor N / 2010 / Improved quality of life, blood pressure, and biochemical status following laparoscopic adrenalectomy for unilateral primary aldosteronism / J Clin Endocrinol Metab 95:1360~1364
Plouin PF / 2004 / Trends in the prevalence of primary aldosteronism, aldosteroneproducing adenomas, and surgically correctable aldosterone-dependent hypertension / Nephrol Dial Transplant 19:774~777
Giacchetti G / 2006 / Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronism : need for a standardized protocol / J Hypertens 24:737~745
Campagnacci R / 2009 / Long-term results of laparoscopic adrenalectomy for primary aldosteronism / J Endocrinol Invest 32:57~62
Sukor N / 2010 / Improved quality of life, blood pressure, and biochemical status following laparoscopic adrenalectomy for unilateral primary aldosteronism / J Clin Endocrinol Metab 95:1360~1364
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