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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 255 - 258 (4page)
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We report 2 cases of chronic estimated glomerular filtration rate (eGFR) decline after unilateral adrenalectomy due to primary aldosteronism. The patients were diagnosed with unilateral adrenal cortical adenoma releasing aldosterone. Two patients were examined for hypertension and hypokalemia. Unilateral laparoscopic adrenalectomy was performed in both cases, and pathology confirmed adrenal cortical adenoma. After adrenalectomy, hypertension and hypokalemia improved to within normal range. However, the eGFR decreased postoperatively, and abdominal computed tomography scan showed decreased kidney size compared to previous images. Kidney biopsy was performed to delineate the exact cause of renal function deterioration and revealed hypertensive changes with chronic interstitial changes, indicating that glomerular hyperfiltration with aldosterone excess masked renal function damage. Physicians have to consider the probability of postadrenalectomy eGFR decline related to chronic hypertensive change.
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등록된 정보가 없습니다.
참고문헌 (11)
참고문헌 신청
Conn JW / 1956 / Aldosterone in clinical medicine;past, present, and future / AMA Arch Intern Med 97:135~144
Teo AE / 2015 / Pregnancy, primary aldosteronism, and adrenal CTNNB1mutations / N Engl J Med 373:1429~1436
Masilamani S / 1999 / Aldo-sterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney / J Clin Invest 104:r19~23
Horita Y / 2001 / Cause of residual hypertension after adrenalectomy in patients with primary aldosteronism / Am J Kidney Dis 37:884~889
Reincke M / 2009 / Risk factors associated with a low glomerular filtration rate in primary aldosteronism / J Clin Endocrinol Metab 94:869~875
Teo AE / 2015 / Pregnancy, primary aldosteronism, and adrenal CTNNB1mutations / N Engl J Med 373:1429~1436
Masilamani S / 1999 / Aldo-sterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney / J Clin Invest 104:r19~23
Horita Y / 2001 / Cause of residual hypertension after adrenalectomy in patients with primary aldosteronism / Am J Kidney Dis 37:884~889
Reincke M / 2009 / Risk factors associated with a low glomerular filtration rate in primary aldosteronism / J Clin Endocrinol Metab 94:869~875
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