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자료유형
학술저널
저자정보
Abdullah Umair (Medical College Aga Khan University Karachi) Nosheen Nasir (Section of Adult Infectious Diseases Department of Medicine Aga Khan University Karachi Pakista)
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care 제36권 제3호
발행연도
2021.8
수록면
256 - 261 (6page)
DOI
10.4266/acc.2020.01158

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Background: Elizabethkingia meningoseptica, formerly known as Chryseobacterium menin gosepticum, is a non-motile, non-fastidious, catalase and oxidase-positive, aerobic, glucose non-fermentative, Gram-negative bacillus that was first defined by Elizabeth O. King in 1959. It has emerged as an opportunistic pathogen that has infected patients in extreme age groups and immunocompromised individuals, especially in intensive care settings. There has been an increased interest in this pathogen due to its increasing occurrence around the world, ubiqui tous nature, and inherent capacity for antimicrobial resistance. Methods: We describe an observational study at a tertiary care center in Karachi, Pakistan, based on patients admitted between January 2013 and December 2018, with E. meningosep tica infections. All patients were confirmed to have a positive clinical culture specimen for E. meningoseptica along with symptoms and signs consistent with infection. Data were collect ed on a structured proforma from the Hospital Information Management Systems. Results: Sixteen patients with E. meningoseptica that met the criteria for infection were iden tified, 13 of whom required admission. Eight patients had bacteremia in addition to confirmed E. meningoseptica infection. Two of the isolates were multi-drug resistant and only sensitive to minocycline. Nine out of 13 patients that were admitted required intubation and mechanical ventilation. The median length of hospital stay was 13 days, and five out of the 13 patients died during the hospital stay. Conclusions: This is the largest case series to date reporting E. meningoseptica infections and highlights the importance of this organism as an emerging nosocomial pathogen.

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