Successful Pre-Operative Local Control of Skin Invasion of Breast Cancer Using a Combination of Systemic Chemotherapy and Mohs Paste

Masahiro Takeuchi; Takefumi Katsuki; Kumiko Yoshida; Kumiko Yoshida; Michinori Iwamura; Toshihiro Inokuchi; Akira Furutani; Tomoe Katoh; Kazuaki Kawano; Keiji Hirata

doi:10.4048/jbc.2021.24.e46

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자료유형: 학술저널

저자정보: Masahiro Takeuchi (Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan.Department of Surgery 1 School of) Takefumi Katsuki (Department of Breast Surgery Kitakyusyu General Hospital Fukuoka Japan.Department of Surgery 1 Scho) Kumiko Yoshida (Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan) Kumiko Yoshida (Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan.) Michinori Iwamura (Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan.Department of Surgery 1 School of Me) Toshihiro Inokuchi (Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan.) Akira Furutani (Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan.) Tomoe Katoh (Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan.) Kazuaki Kawano (Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan.) Keiji Hirata (Department of Surgery School of Medicine University of Occupational and Environmental Health Fukuo)

저널정보: 한국유방암학회 Journal of Breast Cancer Journal of Breast Cancer Vol.24 No.5

발행연도: 2021.10

수록면: 481 - 490 (10page)

DOI: 10.4048/jbc.2021.24.e46

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Locally advanced breast cancer (tumor > 5 cm, widespread infiltration of the skin and muscle, or metastases to lymph nodes) is difficult to resect by surgery, and even when it is resectable, there is a high probability of local recurrence and distant metastasis. Therefore, systemic therapy should be administered first. However, as cutaneous infiltration progresses, the patient's quality of life is impaired by pain, bleeding, presence of exudates, and a foul smelling odor. Treatment with Mohs paste with systemic therapy can control symptoms associated with skin infiltration and can also be expected to decrease tumor volume. Herein, we report a case in which a tumor was resected following Mohs paste and systemic chemotherapy administration, and the skin defect was reconstructed with a latissimus dorsi myocutaneous flap. We also review the literature for previously reported cases of breast cancer involving Mohs paste.

#Breast neoplasms #Drug therapy #General surgery #Myocutaneous flap #Zinc

참고문헌 (45)

참고문헌 신청

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Kuge S / 1996 / Use of metronidazole gel to control malodor in advanced and recurrent breast cancer / Jpn J Clin Oncol 26:207~210

Mohs FE / 1941 / Chemosurgery : a microscopically controlled method of cancer excision / Arch Surg 42:279~295

Mosterd K / 2008 / Surgical excision versus Mohs' micrographic surgery for primary and recurrent basal-cell carcinoma of the face : a prospective randomised controlled trial with 5-years' follow-up / Lancet Oncol 9:1149~1156

Skelton LA / 2009 / The effective treatment of basal cell carcinoma / Br J Nurs 18:346~350

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Masahiro Takeuchi

소속기관 Department of Surgery Yamaguchi Rosai Hospital Yamaguchi Japan.Department of Surgery 1 School of