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논문 기본 정보

자료유형
학술저널
저자정보
Young Eun Chon (Department of Internal Medicine CHA Bundang Medical Center CHA University Seongnam) Seong Yong Park (Big Data Steering Department National Health Insurance Service) Han Pyo Hong (Big Data Center Department of Statistics Yonsei University Wonju College of Medicine) Donghee Son (Biostatistical Consulting and Research Lab Medical Research Collaborating Center Hanyang University) Jonghyun Lee (Department of Medical and Digital Engineering Hanyang University College of Engineering) Eileen Yoon (Department of Internal Medicine School of Medicine Hanyang University) Soon Sun Kim (Department of Gastroenterology Ajou University School of Medicine) Sang Bong Ahn (Department of Internal Medicine Eulji University College of Medicine) Soung Won Jeong (Department of Internal Medicine Soonchunhyang University Seoul Hospital) Dae Won Jun (Department of Internal Medicine School of Medicine Hanyang University)
저널정보
대한간학회 Clinical and Molecular Hepatology Clinical and Molecular Hepatology 제29권 제1호
발행연도
2023.1
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120 - 134 (15page)

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Background/Aims: A comprehensive analysis of trends in the incidence of hepatocellular carcinoma (HCC) is important for planning public health initiatives. We aimed to analyze the trends in HCC incidence in South Korea over 10 years and to predict the incidence for the year 2028. Methods: Data from patients with newly diagnosed HCC between 2008 and 2018 were obtained from Korean National Health Insurance Service database. Age-standardized incidence rates (ASRs) were calculated to compare HCC incidence. A poisson regression model was used to predict the future incidence of HCC. Results: The average crude incidence rate (CR) was 22.4 per 100,000 person-years, and the average ASR was 17.6 per 100,000 person-years between 2008 and 2018. The CR (from 23.9 to 21.2 per 100,000 person-years) and ASR (from 21.9 to 14.3 per 100,000 person-years) of HCC incidence decreased during the past ten years in all age groups, except in the elderly. The ASR of patients aged ≥80 years increased significantly (from 70.0 to 160.2/100,000 person-years; average annual percent change, +9.00%; P<0.001). The estimated CR (17.9 per 100,000 person-years) and ASR (9.7 per 100,000 person-years) of HCC incidence in 2028 was declined, but the number of HCC patients aged ≥80 years in 2028 will be quadruple greater than the number of HCC patients in 2008 (from 521 to 2,055), comprising 21.3% of all HCC patients in 2028. Conclusions: The ASRs of HCC in Korea have gradually declined over the past 10 years, but the number, CR, and ASR are increasing in patients aged ≥80 years.

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