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논문 기본 정보

자료유형
학술저널
저자정보
Sattrachai Prasopdee (Thammasat University) Thittinan Rojthongpond (Thammasat University) Yanwadee Chitkoolsamphan (Thammasat University) Montinee Pholhelm (Thammasat University) Siraphatsorn Yusuk (Thammasat University) Junya Pattaraarchachai (Thammasat University) Kritiya Butthongkomvong (Udonthani Cancer Hospital, Ministry of Public Health) Jutharat Kulsantiwong (Udon Thani Rajabhat University) Teva Phanaksri (Thammasat University) Anthicha Kunjantarachot (Thammasat University) Smarn Tesana (Thammasat University) Thanakrit Sathavornmanee (Chonburi Hospital, Ministry of Public Health) Veerachai Thitapakorn (Thammasat University)
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases Parasites, Hosts and Diseases Vol.61 No.4
발행연도
2023.11
수록면
463 - 470 (8page)

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This study aimed to identify the recent risk factors for Opisthorchis viverrini infection and cholangiocarcinoma (CCA) to improve disease prevention. The participants were divided into the following 3 groups based on their health status: healthy control (nonOV and nonCCA), those with O. viverrini infection (OV), and those with CCA. A questionnaire was used to explore their lifestyle and behaviors. Multivariate logistic regression and backward elimination were used to identify the significant risk factors. The results showed that the significant risk factors for both O. viverrini infection and CCA were age>50 years (odd ratio (OR)=8.44, P<0.001, 95% confidence intervals (CI) 2.98–23.90 and OR=43.47, P=0.001, 95% CI 14.71-128.45, respectively) and raw fish consumption (OR=8.48, P< 0.001, 95% CI 3.18-22.63 and OR=3.15, P=0.048, 95% CI 1.01-9.86, respectively). A history of O. viverrini infection was identified as an additional risk factor for CCA (OR=20.93, P=0.011, 95% CI 2.04-215.10). This study provided an update on the risk factors for O. viverrini infection and CCA. Asymptomatic patients with O. viverrini infection, particularly those>50 years old, should be carefully monitored to prevent CCA.

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