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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.12
- 수록면
- 231 - 241 (11page)
- DOI
- 10.22889/KJP.2023.54.4.231
이용수
초록· 키워드
오류제보하기
This study investigated the efficacy of Theracurmin Super, a curcumin formulation with enhanced bioavailability, in the treatment of osteoarthritis. An in vivo model of osteoarthritis induced by monosodium iodoacetate (MIA) was used to assess the analgesic and weight-bearing effects of Theracurmin Super alone and in combination with glucosamine. The results demonstrated that both Theracurmin Super monotherapy and combination therapy significantly improved pain threshold and weight-bearing capacity compared to the control group. The combination therapy showed even greater benefits. Moreover, both treatment groups exhibited improvements in cartilage damage, with reduced severity of cartilage loss and destruction. Evaluation of bone volume and surface damage in the same test model indicated enhanced bone health in the treatment groups. Additionally, the combination therapy group exhibited a decrease in factors associated with inflammation and cartilage damage in joint tissues. These findings suggest that Theracurmin Super, whether used alone or in combination with glucosamine, holds promise as a treatment for osteoarthritis.
목차
Abstract
재료 및 방법
결과 및 고찰
결론
인용문헌
참고문헌 (36)
참고문헌 신청
Loeser, R. F., Goldring, S. R., Scanzello, C. R. and Goldring, M. B. (2012) Osteoarthritis: A disease of the joint as an organ. Arthritis Rheum. 64: 1697-1707.
Sen, R. and Hurley, J. A. (2022) Osteoarthritis. Statpearls [Internet] https://www.ncbi.nlm.nih.gov/books/NBK482326/ Accessed 3 March 2023.
Azad, C. S., Singh, A. K., Pandey, P., Singh, M., Chaudhary, P., Tia, N., Rastogi, A. and Gambhir, I. S. (2017) Osteoarthritis in india: an epidemiologic aspect. Int. J. Recent. Sci. Res. 8: 20918-20922.
Korea Centers for Disease Control and Prevention (2017) National health statistics: from the seventh-II Korean National Health and Nutrition Examination Survey (KNHANES VII- 2). Health Statistics Report. Sejong: Health Policy Department, Ministry of Health and Welfare; 2018 December. Report No.: 11-1351159-000027-10.
Kim, H. A. (2007) The Management of arthritis. J. Korean Med. Assoc. 50: 743-750.
Sen, R. and Hurley, J. A. (2022) Osteoarthritis. Statpearls [Internet] https://www.ncbi.nlm.nih.gov/books/NBK482326/ Accessed 3 March 2023.
Azad, C. S., Singh, A. K., Pandey, P., Singh, M., Chaudhary, P., Tia, N., Rastogi, A. and Gambhir, I. S. (2017) Osteoarthritis in india: an epidemiologic aspect. Int. J. Recent. Sci. Res. 8: 20918-20922.
Korea Centers for Disease Control and Prevention (2017) National health statistics: from the seventh-II Korean National Health and Nutrition Examination Survey (KNHANES VII- 2). Health Statistics Report. Sejong: Health Policy Department, Ministry of Health and Welfare; 2018 December. Report No.: 11-1351159-000027-10.
Kim, H. A. (2007) The Management of arthritis. J. Korean Med. Assoc. 50: 743-750.
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