지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.3
- 수록면
- 27 - 35 (9page)
- DOI
- 10.35986/me.2024.22.1.27
이용수
초록· 키워드
오류제보하기
Background: Associations between metabolic abnormalities and poor treatment outcomes in bipolar disorder (BD) have been reported. This study examined the influence of metabolic abnormalities on remission in Korean inpatients with BD.
Methods: This study retrospectively reviewed the chart of 128 adult patients with BD who were hospitalized at a university hospital in Korea. The collected data included fasting plasma glucose, total cholesterol, triglycerides, and high-density lipoprotein levels at admission, as well as height, weight, and blood pressure measurements. The prevalence of metabolic abnormalities was compared between the remission (17-item Hamilton Depression Rating Scale score of ≤7 and Young Mania Rating Scale score of <8) and nonremission groups.
Results: Prevalence of hyperglycemia and hypertriglyceridemia significantly differed between the nonremission and remission groups. Multivariate analysis revealed hyperglycemia as the only significant risk factor for nonremission in subjects with mood and manic/hypomanic episodes.
Conclusion: The study findings reveal a negative effect of hyperglycemia on the treatment outcome of BD. Clinical attention to metabolic abnormalities, specifically insulin resistance and hyperglycemia, is recommended during early stages of the disease.
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