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논문 기본 정보

자료유형
학술저널
저자정보
Krishnamoorthy Suhas (Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China) Tang Casey Tze-Lam (Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China) Hsu Warrington Wen-Qiang (Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China) Li Gloria Hoi-Yee (The Hong Kong Polytechnic University, Hong Kong, China) Sing Chor-Wing (Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China) Zhang Xiaowen (Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China) Tan Kathryn Choon-Beng (The University of Hong Kong, Hong Kong, China) Cheung Bernard Man-Yung (The University of Hong Kong, Hong Kong, China) Wong Ian Chi-Kei (Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China) Kung Annie Wai-Chee (The University of Hong Kong, Hong Kong, China) Cheung Ching-Lung
저널정보
대한골다공증학회 Osteoporosis and Sarcopenia English Vol.10 No.2
발행연도
2024.6
수록면
60 - 65 (6page)
DOI
10.1016/j.afos.2024.05.002

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Objectives: Type 2 diabetes mellitus (T2DM) shares a complex relationship with bone metabolism and few studies investigated the effect of impaired bone health on the risk of T2DM. This study was conducted to investigate the association between hip fractures and the risk of incident T2DM. Methods: This is a retrospective cohort study using data from the real-world hip fracture cohort. Hong Kong Chinese patients aged ≥ 65 years without T2DM who were admitted to public hospitals due to a fall between 2008 and 2015 were included in the study. Patients who sustained falls with and without hip fractures were matched by propensity score (PS) at a 1:1 ratio. Competing risk regression was used to evaluate the association between hip fracture and incident T2DM, with death being the competing event. Results: A total of 23,314 hip fracture cases were matched to 23,314 controls. The median follow-up time was 5.09 years. The incidence rate of T2DM was 11.947 and 14.505 per 1000 person-years for the hip fracture and control group respectively. After accounting for the competing risk of death, the hip fracture group had a significantly lower risk of developing T2DM (HR: 0.771, 95% CI: 0.719–0.827). Similar results were observed in all subgroups after stratification by age and sex. Conclusions: Hip fracture was found to be associated with a reduced risk of T2DM. These findings provide insight into the topic of bone and glucose metabolism and prompt further research in evaluating the role of bone health in the management of T2DM.

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