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논문 기본 정보

자료유형
학술저널
저자정보
Shin Sanghee (Department of Pediatrics, Chung-Ang University Hospital, Seoul, Korea.) Lee Ji Young (Department of Pediatrics, Chuncheon Sacred Heart Hospital, Hallym University School of Medicine, Chuncheon, Korea.) Cho Hyun (Academic Research Service Headquarter, LSK Global PS, Seoul, Korea.) Kim Minji (Department of Pediatrics, Chungnam National University Sejong Hospital, Sejong, Korea.) Kim Sukyung (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.Environmental Health Center for Atopic Diseases, Samsung Medical Center, Seoul, Kor) Jang Sehun (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.) Song Jeongmin (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.) Kim Jihyun (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.Department of Health Sciences and Technology, Samsung Advanced Institute for Health) Kim Seonwoo (Academic Research Service Headquarter, LSK Global PS, Seoul, Korea.) Ahn Kangmo (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.Department of Health Sciences and Technology, Samsung Advanced Institute for Health)
저널정보
대한천식알레르기학회(구 대한알레르기학회) Allergy, Asthma & Immunology Research AAIR Vol.16 No.3
발행연도
2024.5
수록면
300 - 307 (8page)
DOI
10.4168/aair.2024.16.3.300

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초록· 키워드

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Severe atopic dermatitis (AD) is not a localized cutaneous disease, but a systemic disease that often accompanies comorbidities. In this nationwide population-based study, we aimed to analyze the prevalence of severe AD and chronic systemic diseases in Koreans aged ≤ 20 years between 2011 and 2019 using the data from the Korean Health Insurance Review and Assessment Service. Total AD and severe AD were defined according to the International Classification of Diseases-10 code L20. In children aged 6–20 years, the prevalence of severe AD significantly increased from 0.02% in 2011 to 0.04% in 2019 (P for trend < 0.001), with the ratio of severe AD to total AD increasing from 0.76% in 2011 to 1.10% in 2019 (P for trend < 0.001). The prevalence rates of severe AD significantly increased between 2011 and 2019 in children aged 6–12 years (P for trend < 0.05) and 13–18 years (P for trend < 0.001). Severe AD was more frequently found in males than in females each year (all P < 0.001, from 2011 to 2019). During the period from 2011 to 2019, the prevalence rate of chronic systemic diseases was higher in subjects with severe AD than in those without AD (P < 0.001) or with mild-to-moderate AD (P < 0.001). In conclusion, our results suggest that the prevalence of severe AD is increasing in Korean children and adolescents and is higher in males and older age groups. Moreover, severe AD is associated with chronic systemic diseases. Therefore, more attention should be paid to managing severe AD.

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