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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.7
- 수록면
- 1 - 15 (15page)
- DOI
- https://doi.org/10.3802/jgo.2024.35.e96
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초록· 키워드
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Objective: This study aimed to comprehensively analyze the clinical characteristics andtreatment status of Chinese small cell carcinoma of the ovar y hypercalcemic type (SCCOHT)patients, providing insights into this unique population and comparing findings withinternational literature.
Methods: Through a meta-analysis, we collected data from published case reports andrecords from the Obstetrics & Gynecology Hospital of Fudan University. Demographicinformation, clinical presentations, tumor attributes, treatment modalities, and sur vivaloutcomes were extracted and examined alongside relevant global studies.
Results: The analysis encompassed 80 Chinese SCCOHT patients, of which 62 from33 previously reported literatures, and the other 18 were from Obstetrics & GynecologyHospital of Fudan University. In 62 cases with stage information, A total of 25 tumors wereInternational Federation of Gynecology and Obstetrics stage I, 3 were stage II, 19 were stageIII, and 15 were stage IV. Most patients received surger y and chemotherapy, but regimenswere varied. Median follow-up was 10 months (range=4–120). Elevated carbohydrate antigen125 and serum calcium levels were consistent findings. Recurrence rates were notable,especially among stage I patients. Platinum-based chemotherapy, paclitaxel and carboplatin(n=11, 13.4%), constituted common treatment regimens.
Conclusion: This study obser ved demographic and clinical similarities with internationaldatasets. And the findings emphasize the urgency for innovative therapeutic approaches toimprove outcomes in SCCOHT patients. Continued research efforts are essential to enhancethe knowledge surrounding this rare malignancy and to optimize its clinical management.
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