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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.4 No.3
- 발행연도
- 1999.9
- 수록면
- 163 - 166 (4page)
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초록· 키워드
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Previously, the methanolic extract of Paeonia lactiflora seeds was shown to have strong inhibitory activity against soybean lipoxygenase (SLO). Four phenolic compounds were isolated from the seeds by solvent fractionation, Sephadex LH-20 column chromatography and preparative HPLC, and three of them showed strong SLO inhibition and were characterized as trans-resveratrol, ε-viniferin and luteolin by UV, IR, ¹H-NMR, ¹³C-NMR and MS spectrometry. trans-Resveratrol (IC_(50)=1.02 μM), ε-viniferin (IC_(50)=O.81 μM) and luteolin (IC_(50)=10.01 μM), first found in the above seeds, exhibited a potent SLO inhibitory activity although their activity was lower than that of a well-known lipoxygenase inhibitor, nordihydroguaiaretic acid (NDGA) (IC_(50)=0.57 μM). These results suggest that Paeonia lactiflora seeds, now an unused plant seed, may be developed into useful sources of anti-inflammatory drugs.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
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UCI(KEPA) : I410-ECN-0101-2009-511-018075179