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자료유형
학술저널
저자정보
저널정보
대한생물치료정신의학회 생물치료정신의학 생물치료정신의학 제4권 제1호
발행연도
1998.6
수록면
103 - 117 (15page)

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초록· 키워드

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Sleep disorders are a major complaint and are among the most common reasons for consulting a doctor. Patient may experience difficulties in falling asleep, frequent awakenings during the night, or early morning awakening. The result of a disturbed night's sleep is an impairment of daytime wellbeing. The loss of the restorative function of sleep in this way leads to impaired' daytime performance and affects vital function. As a direct consequence of this interdependence of sleep and daytime wellbeing, insomnia is a 24-hour problem and the treatment of insomnia may now be considered a 24-hour therapy.
Although treatment of insomnia should be an individualized treatment approach, besides behavioral treatment of insomnia, sedative hypnotics certainly occupy a place in the treatment of insomnia.
The ideal hypnotic should induce and maintain sleep, respect the physiology of sleep, improve daytime wellbeing, induce minimal or no side effects, and be devoid of dependence and abuse potential. There, however, is no such ideal hypnotic. Although effective hypnotics are available, their use still leaves the prescribing doctor with unresolved problems. Some of the hypnotics are very potent in inducing sleep but they do not maintain sleep overnight; others are effective in inducing and maintaining sleep, but leave patients with residual effects on awakening, which interfere with their daytime mental and physical functioning.
The short-acting benzodiazepines appear to have significant advantages over the long-acting agents in several areas including daytime sedation, propensity for falls in the elderly, and respiratory depression. And short-acting agents may be more effective on the first night of administration compared with long-acting agents such as flurazepam. These reasons have been significant in leading to their widespread popularity. In contrast, the long-acting agents may be preferable when daytime sedation is desired. They are often associated with a delayed and milder withdrawal sleep disturbance. When the short-acting agents are given, however, this difficulty can be minimized by tapering the dose.
This paper reviews the proper use of sleeping pills in the primary care setting in the context of current controversy involving sedative hypnotics in general and benzodiazepine hypnotics in particular. It is concluded if the physician feels a patient's insomnia warrants symptomatic relief with medication, it is appropriate toprescribe the lowest effective dose of a hypnotic for several nights. depending on the circumstances, the physician can specify either a short-acting or a long-acting hypnotic.
Hypnotic medication is indicated for the treatment of transient and short-term insomnia. It could be also used for chronic insomnia as adjunctive treatment.
Pharmacotherapy for insomnia is often not only appropriate and safe, but highly desirable if it is selected and used properly.

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