지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.86 No.6
- 발행연도
- 2014.6
- 수록면
- 314 - 318 (5page)
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초록· 키워드
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Purpose: Laparoscopic splenectomy (LS) for pediatric chronic immune thrombocytopenic purpura (ITP) patients has recently become widespread. However, its long-term result is rarely reported in children.
Methods: We retrospectively analyzed the patients who underwent LS for pediatric chronic ITP from June 1998 to April 2007.
Results: There were 18 patients (14 male and 4 female) with mean age 9.5 ± 3.8 years. 14 complete response, 3 partial response, and 1 no response were occurred. During the 82-month median follow-up period, 9 patients maintained in a remission state without any additional treatment, and 9 patients relapsed. In a comparative analysis of the relapse group and no relapse group, hospital stays were longer in the relapse group and the preoperative platelet counts and platelet counts at 1 month post were lower in relapse group. A relapse-free survival among 17 patients who achieved partial or complete responses following LS showed 76.5%, 61.8%, and 33.0% at 1-, 5-, and 10-year following LS, respectively.
Conclusion: Although LS in pediatric chronic ITP patients had excellent results immediately after surgery, careful follow up is needed due to late relapse even when a complete response has been noted for several years.
Methods: We retrospectively analyzed the patients who underwent LS for pediatric chronic ITP from June 1998 to April 2007.
Results: There were 18 patients (14 male and 4 female) with mean age 9.5 ± 3.8 years. 14 complete response, 3 partial response, and 1 no response were occurred. During the 82-month median follow-up period, 9 patients maintained in a remission state without any additional treatment, and 9 patients relapsed. In a comparative analysis of the relapse group and no relapse group, hospital stays were longer in the relapse group and the preoperative platelet counts and platelet counts at 1 month post were lower in relapse group. A relapse-free survival among 17 patients who achieved partial or complete responses following LS showed 76.5%, 61.8%, and 33.0% at 1-, 5-, and 10-year following LS, respectively.
Conclusion: Although LS in pediatric chronic ITP patients had excellent results immediately after surgery, careful follow up is needed due to late relapse even when a complete response has been noted for several years.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (17)
참고문헌 신청
1. [학술지(정기간행물)] - Cines DB. / 2002 / Immune thrombocytopenic purpura / N Engl J Med 346 : 995 ~ 1008
2. [학술지(정기간행물)] - McMillan R. / 1981 / Chronic idiopathic thrombocytopenic purpura / N Engl J Med 304 : 1135 ~ 1147
3. [학술지(정기간행물)] - Delaitre B. / 1991 / Splenectomy by the laparoscopic approach. Report of a case / Presse Med 20 : 2263 ~
4. [학술지(정기간행물)] - Tulman S. / 1993 / Pediatric laparoscopic splenectomy / J Pediatr Surg 28 : 689 ~ 692
5. [학술지(정기간행물)] - Friedman RL. / 1996 / Laparoscopic splenectomy for ITP. The gold standard / Surg Endosc 10 : 991 ~ 995
2. [학술지(정기간행물)] - McMillan R. / 1981 / Chronic idiopathic thrombocytopenic purpura / N Engl J Med 304 : 1135 ~ 1147
3. [학술지(정기간행물)] - Delaitre B. / 1991 / Splenectomy by the laparoscopic approach. Report of a case / Presse Med 20 : 2263 ~
4. [학술지(정기간행물)] - Tulman S. / 1993 / Pediatric laparoscopic splenectomy / J Pediatr Surg 28 : 689 ~ 692
5. [학술지(정기간행물)] - Friedman RL. / 1996 / Laparoscopic splenectomy for ITP. The gold standard / Surg Endosc 10 : 991 ~ 995
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