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논문 기본 정보

자료유형
학술저널
저자정보
Jung-Ah Do (Ministry of Food and Drug Safety) Jung Yeon Kim (Ministry of Food and Drug Safety) Ji Yeon Choi (Ministry of Food and Drug Safety) Ji Hyun Lee (Ministry of Food and Drug Safety) Hyung Joo Kim (Ministry of Food and Drug Safety) Eunyoung Noh (Ministry of Food and Drug Safety) So-Hyun Cho (Ministry of Food and Drug Safety) Chang-Yong Yoon (Ministry of Food and Drug Safety) Woo-Seong Kim (Ministry of Food and Drug Safety)
저널정보
한국분석과학회 분석과학 분석과학 제28권 제2호
발행연도
2015.4
수록면
86 - 97 (12page)

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Recently, the consumption of dietary supplements has increased because of people’s greater interest in health. Unfortunately, the sales of dietary supplements containing unauthorized substances such as drugs have also increased. We developed a rapid, accurate method for the simultaneous determination of antihistamines using liquid chromatography tandem mass spectrometry with a multiple reaction monitoring mode. The limit of detection (LOD) and limit of quantification (LOQ) of the instrument used in this method were in the ranges 0.0003-0.3 and 0.0009-0.6 μg mL?1, respectively. The linearity of the method was > 0.99. The precision levels of the method were 0.1-9.8% (intra-day) and 0.3-9.6% (inter-day), and the levels of accuracy of the method were 82.7-115.0% (intra-day) and 84.3-113.0% (inter-day). The mean of recovery of the method was in the range of 83.9-117.9% and the RSD of the stability was less than 5.9%.

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Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
References

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UCI(KEPA) : I410-ECN-0101-2016-433-001460959