지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Alcoholism is a significant health problem in the world. The liver is the first and primary target organ for alcohol metabolism. Alcohol dehydrogenase and aldehyde dehydrogenase play important roles in the metabolism of alcohol and aldehyde. In this study, I aimed to investigate the eliminatory effects of a Phellinus spp. extract on alcohol metabolism in drunken Sprague-Dawley (SD) rats. Male SD rats were given Phellinus spp. extract at 30 min after 40% (5 g/kg) alcohol ingestion. To assay the effect of Phellinus spp. extract on blood alcohol concentration, blood samples were taken from the tail vein at 1, 3 and 5 h after alcohol ingestion. The concentrations of alcohol, alcohol dehydrogenase, and aldehyde dehydrogenase in Phellinus spp. extract treated rat were significantly lower than that of the control with a time-dependent manner. In addition, the alanine aminotransferase and aspartate aminotransferase activities of Phellinus spp. extract-treated groups were altered compared to those of the control group. These results suggest that Phellinus spp. extract intake can have a positive effect on the reduction of alcohol, alcohol dehydrogenase, and aldehyde dehydrogenase concentrations in the blood and may alleviate acute alcohol-induced hepatotoxicity by altering alcohol metabolic enzyme activities. Phellinus spp. extract is thus a good nutraceutical candidate.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (25)
참고문헌 신청
[학술지(정기간행물)] - Baldi E / 1993 / Serum malondialdehyde and mitochondrial aspartate aminotransferase activity as markers of chronic alcohol intake and alcoholic liver disease / Ital J Gastroenterol 258 : 429 ~ 432
[학술지(정기간행물)] - Choi JS / 2006 / Glycoprotein isolated from Acanthopanax senticosus protects against hepatotoxicity induced by acute and chronic alcohol treatment / Biol Pharm Bull 292 : 306 ~ 314
[학술지(정기간행물)] - Dai YC / 2010 / Current advances in Phellinus sensu lato: medicinal species, functions, metabolites and mechanisms / Appl Microbiol Biotechnol 875 : 1587 ~ 1593
[학술지(정기간행물)] - Guidot DM / 2002 / Chronic ethanol ingestion increases susceptibility to acute lung injury: role of oxidative stress and tissue remodeling / Chest 1226 (Suppl) : 309S ~ 314S
[학술지(정기간행물)] - Hur JM / 2004 / Antibacterial effect of Phellinus linteus against methicillinresistant Staphylococcus aureus / Fitoterapia 756 : 603 ~ 605
[학술지(정기간행물)] - Choi JS / 2006 / Glycoprotein isolated from Acanthopanax senticosus protects against hepatotoxicity induced by acute and chronic alcohol treatment / Biol Pharm Bull 292 : 306 ~ 314
[학술지(정기간행물)] - Dai YC / 2010 / Current advances in Phellinus sensu lato: medicinal species, functions, metabolites and mechanisms / Appl Microbiol Biotechnol 875 : 1587 ~ 1593
[학술지(정기간행물)] - Guidot DM / 2002 / Chronic ethanol ingestion increases susceptibility to acute lung injury: role of oxidative stress and tissue remodeling / Chest 1226 (Suppl) : 309S ~ 314S
[학술지(정기간행물)] - Hur JM / 2004 / Antibacterial effect of Phellinus linteus against methicillinresistant Staphylococcus aureus / Fitoterapia 756 : 603 ~ 605
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
알코올 사용장애의 역학과 예방 정책
신경정신의학
2019 .01
-
β-glucan 함량과 관능검사를 통한 상황버섯 품질기준 모색
대한본초학회지(본초분과학회지)
2017 .01
-
Perceptions About Alcohol Harm and Alcohol-control Strategies Among People With High Risk of Alcohol Consumption in Alberta, Canada and Queensland, Australia
예방의학회지
2018 .01
-
우리나라 알코올 규제 정책의 이행 현황과 향후 과제
보건교육건강증진학회지
2021 .03
-
건강증진 관점에서 본 음주와 음주폐해 감소 정책
보건교육건강증진학회지
2016 .10
-
우리나라 국민의 공공장소에서의 음주경험과 음주폐해: 레저시설을 중심으로
보건교육건강증진학회지
2019 .06
-
Global and regional impacts of alcohol use on public health: Emphasis on alcohol policies
Clinical and Molecular Hepatology
2020 .01
-
상황버섯 균사체 추출물의 숙취해소 효과에 관한 연구
Korean Journal of Veterinary Research(대한수의학회지)
2017 .02
-
The Extract of Limonium tetragonum Protected Liver against Acute Alcohol Toxicity by Enhancing Ethanol Metabolism and Antioxidant Enzyme Activities
Natural Product Sciences
2015 .03
-
한국 성인 남성의 알코올 분해의 약동학적 특징 및영향요인
신경정신의학
2015 .01
-
The effects of moderate alcohol consumption on non-alcoholic fatty liver disease
Clinical and Molecular Hepatology
2023 .02
-
Alcohol-related liver disease and liver transplantation
고신대학교 의과대학 학술지
2022 .06
-
문제음주수준이 음주의 간접폐해에 미치는 영향 : 음주에 대한 기대의 조절효과를 중심으로
보건교육건강증진학회지
2016 .09
-
Effects of screening and brief intervention on alcohol consumption in an emergency department
Clinical and Experimental Emergency Medicine
2020 .01
-
The effect of moderate alcohol drinking in nonalcoholic fatty liver disease
Clinical and Molecular Hepatology
2020 .01
-
음주폐해 감소를 위한 포괄적 근거기반 지역사회 전략: NoMAD 프로젝트
중독정신의학
2023 .04
-
Alcohol Consumption, Aldehyde Dehydrogenase 2 Gene Polymorphisms, and Cardiovascular Health in Korea
Yonsei Medical Journal
2017 .07
-
음주의 발암성에 대한 국민 인지도와 음주 규제 정책 지지도
보건교육건강증진학회지
2023 .12
-
Effect of herbal extracts on alcohol induced erectile dysfunction in rat
한국실험동물학회 학술발표대회 논문집
2018 .07
-
음주 관련 신문기사 제목에 나타난 의미 구성과 공중보건학적 함의: 의미연결망 분석의 적용
보건교육건강증진학회지
2021 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2017-510-000852091