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커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.9
- 수록면
- 115 - 127 (13page)
이용수
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초록· 키워드
오류제보하기
Since 1990 when Wolff and co-authors proved that both RNA and DNA expression vectors containing interest gene were directly injected into mouse muscle and expressed the protein in vivo, the concept of gene vaccine has been broadly tested in the vaccine field. However, due to the limitations of technology and the misconception about RNA, most previous studies have focused on the DNA vaccine. Recently, the RNA vaccine has emerged as a new game-changing disruptive innovation technology in the vaccine field. This review has covered the characteristics of the RNA vaccine, including its strengths and weaknesses. Finally, we have suggested future directions for the RNA vaccine.
목차
I. INTRODUCTION
II. DNA 백신의 문제점 및 RNA 백신의 특징
III. RNA 백신의 구조
IV. RNA 백신 개발을 위한 플랫폼
V. mRNA 백신의 면역학적 특징
VI. RNA 백신의 활용
VII. RNA 백신 제작
VIII. RNA 백신 접종 경로 및 숙주 전달
IX. RNA 백신의 안정성(stability)
X. CONCLUSION
REFERENCES
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UCI(KEPA) : I410-ECN-0101-2017-475-001400540