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논문 기본 정보

자료유형
학술저널
저자정보
Jae Woong Sull (Eulji University) Eun Na Koh (Yonsei University) Sung Kweon Cho (Yonsei University College of Medicine) Hyung-Joon Bae (Daejeon Institute of Science and Technology) Sun Ha Jee (Yonsei University)
저널정보
대한의생명과학회 대한의생명과학회지 대한의생명과학회지 제23권 제3호
발행연도
2017.9
수록면
201 - 207 (7page)

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초록· 키워드

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Measuring the pulse wave velocity (PWV) is a non-invasive method for evaluating the stiffness of the vessel wall. While previous studies investigated the association of uric acid level with arterial stiffness, most did not consider smoking status and obesity as covariates. The objective of this study was to investigate the relationship between uric acid levels and arterial stiffness, considering smoking status and obesity. We studied 3390 subjects (1940 males and 1450 females). Abnormal PWV was also defined as the highest quartile of values in the subjects. Data were analyzed using Pearson correlation, t-test, and multiple regression analysis. Approximately 41.9% of men and 3.7% of women were current smokers. Prevalence of hypertension was 11.4% in men and 7.0% in women. In women, hyperuricemia was associated with abnormal PWV (OR 1.58; 95% CI 1.03~2.43). Hyperuricemia was also associated with abnormal PWV (OR 2.37; 95% CI 1.01~5.59) in non- or light male smokers with normal blood pressure. This study suggests that uric acid is associated with arterial stiffness in women and non-smoking men.

목차

INTRODUCTION
SUBJECTS AND METHODS
RESULTS
DISCUSSION
REFERENCES

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