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논문 기본 정보

자료유형
학술저널
저자정보
Zhengqiu Zhu (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Lingshan Chen (Departments of Radiology Affiliated Hospital of Nanjing University of Chinese Medicine) Wenjun Liu (School of Mathematics and Statistics Nanjing University of Information Science and Technology) Yiyun Wu (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Chong Zou (Department of Cardiology Affiliated Hospital of Nanjing University) Xinyi Zhang (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Shanshan He (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Yinping Wang (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Bixiao Shen (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Xuehui Ma (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Hui Gao (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Yun Luan (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine) Hui Huang (Departments of Ultrasound Affiliated Hospital of Nanjing University of Chinese Medicine)
저널정보
대한초음파의학회 ULTRASONOGRAPHY ULTRASONOGRAPHY Vol.41 No.3
발행연도
2022.7
수록면
462 - 472 (11page)
DOI
10.14366/usg.21197

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Purpose: The present study investigated the association between Systematic COronary Risk Evaluation (SCORE)-estimated cardiovascular risk and carotid stiffening in a middle-aged population using ultrafast pulse wave velocity (ufPWV).Methods: This study enrolled 683 participants without known cardiovascular disease or diabetes mellitus who underwent ufPWV measurements. Clinical interviews, physical examinations, laboratory findings, carotid intima-media thickness (cIMT), pulse wave velocity (PWV) at the beginning of systole (PWV-BS), and PWV at the end of systole (PWV-ES) were assessed. Each participant underwent an assessment of SCORE risk based on major cardiovascular risk factors (CVRFs), including age, sex, smoking, systolic blood pressure (SBP), and total cholesterol (TC). Crude and adjusted odds ratios (ORs) with 95% confidence intervals and ordinal logistic regression were used. Overall CVRFs were adjusted to assess ORs.Results: cIMT and carotid stiffening in PWV-BS and PWV-ES were significantly different between sex subgroups (all P<0.05), but only PWV-ES increased gradually in age and SCORE-estimated risk subgroups (all P<0.05). Compared with cIMT (r=0.388, P<0.001) and PWV-BS (r=0.159, P<0.001), PWV-ES was more strongly correlated with SCORE categories (r=0.405, P<0.001). Higher PWV-ES values were associated with SCORE categories independently of sex, SBP, TC, and smoking in moderate-risk and high-risk subgroups (OR, 1.63; P<0.001 and OR, 2.12; P=0.024, respectively), but were not independent of age in all risk subgroups (all P>0.05).Conclusion: Carotid stiffening quantified by ufPWV is linked to SCORE categories, and elevated PWV-ES may aid in cardiovascular risk stratification.

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