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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제52권 제5호
- 발행연도
- 2018.1
- 수록면
- 290 - 297 (8page)
이용수
초록· 키워드
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Background: Chronic placental inflammation (CPI) has been implicated in the pathogenesis of diseases in premature infants, whereas retinopathy of prematurity (ROP) is a major complication primarily affecting preterm and very low-birth-weight (VLBW) infants. This study aims to investigate the association between CPI and ROP in VLBW infants. Methods: We performed a retrospective review of clinical records of VLBW infants born between 2013 and 2016. Placental pathology findings including CPI cases were analyzed using logistic regression to study infants’ morbidities and other clinical characteristics. Results: A total of 402 infants with a mean (standard deviation) gestational age of 28.5 (2.8) weeks and birth weight of 1,027.2 (304.4) g were included. The incidence of ROP was 24.1%. CPI was found in 90 infants (22.4%), among which 28.9% (26 of 90) developed ROP, and 21.1% (19 of 90) underwent laser photocoagulation. Lower gestational age, lower birth weight, longer duration of oxygen supply, and presence of CPI were associated with the development of ROP. After adjustment for gestational age, birth weight, sex, duration of oxygen supply, and other overlapping placental pathology, CPI was associated with the odds for type 1 ROP that required laser photocoagulation (adjusted odds ratio, 2.739; 95% confidence interval, 1.112 to 6.749; p = .029). Conclusions: CPI was associated with severe ROP requiring treatment with laser photocoagulation in VLBW infants.
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등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
Galinsky R / 2013 / The consequences of chorioamnionitis: preterm birth and effects on development / J Pregnancy 2013:412831
Morgan TK / 2016 / Role of the placenta in preterm birth: a review / Am J Perinatol 33:258~266
Redline RW / 2008 / Placental pathology: a systematic approach with clinical correlations / Placenta 29(Suppl A):S86~S91
Lee J / 2013 / Chronic chorioamnionitis is the most common placental lesion in late preterm birth / Placenta 34:681~689
Kim CJ / 2015 / Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance / Am J Obstet Gynecol 213(4 Suppl):S29~S52
Morgan TK / 2016 / Role of the placenta in preterm birth: a review / Am J Perinatol 33:258~266
Redline RW / 2008 / Placental pathology: a systematic approach with clinical correlations / Placenta 29(Suppl A):S86~S91
Lee J / 2013 / Chronic chorioamnionitis is the most common placental lesion in late preterm birth / Placenta 34:681~689
Kim CJ / 2015 / Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance / Am J Obstet Gynecol 213(4 Suppl):S29~S52
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