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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 272 - 278 (7page)
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초록· 키워드
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Purpose: To compare long-term refractive outcomes associated with intravitreal anti-vascular endothelial growthfactor (VEGF) versus laser photocoagulation treatment for retinopathy of prematurity (ROP). Methods: A total of 52 eyes from 27 ROP patients treated at two tertiary referral-based hospitals from August2006 to December 2013 were reviewed. The primary outcome was refractive error measured at the age of 4years, accounting for within-patient inter-eye correlation. Secondary outcomes included the recurrence rate andtreatment complications. Results: The mean age at refraction was 4.7 ± 0.3 years in the laser group (n = 30) and 4.4 ± 0.3 years in the anti-VEGF group (n = 22). No significant differences were noted in gestational age, birthweight, post-menstrual ageat treatment, or ROP stage/zone distribution between groups. Mean spherical equivalent was also not significantlydifferent (-1.0 diopters in the laser group and -0.3 diopters in the injection group, p = 0.603). Clustered regressionanalysis revealed that only gestational age was significantly correlated with mean spherical equivalent (p <0.001; 95% confidence interval, -0.007 to -0.002). Recurrence was noted in four eyes (13.3%) in the laser group,but this difference was not significant (p = 0.128). There were no major systemic complications reported in eithergroup. Conclusions: Treatment type, whether laser or anti-VEGF injection, does not appear to influence long-term refractiveoutcomes in ROP. Concern regarding refractive outcomes should not be the most important factor whenselecting ROP treatment modality.
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참고문헌 (34)
참고문헌 신청
Blencowe H / 2013 / Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010 / Pediatr Res 74(Suppl 1):35~49
Kushner BJ / 1977 / Retrolental fibroplasia. II. Pathologic correlation / Arch Ophthalmol 95:29~38
Darlow BA / 2015 / Retinopathy of prematurity : new developments bring concern and hope / J Paediatr Child Health 51:765~770
Goggin M / 1991 / Childhood blindness in the Republic of Ireland : a national survey / Br J Ophthalmol 75:425~429
Hoogerwerf A / 2010 / Incidence of retinopathy of prematurity over the last decade in the Central Netherlands / Neonatology 98:137~142
Kushner BJ / 1977 / Retrolental fibroplasia. II. Pathologic correlation / Arch Ophthalmol 95:29~38
Darlow BA / 2015 / Retinopathy of prematurity : new developments bring concern and hope / J Paediatr Child Health 51:765~770
Goggin M / 1991 / Childhood blindness in the Republic of Ireland : a national survey / Br J Ophthalmol 75:425~429
Hoogerwerf A / 2010 / Incidence of retinopathy of prematurity over the last decade in the Central Netherlands / Neonatology 98:137~142
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