지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제3권 제1호
- 발행연도
- 2015.1
- 수록면
- 47 - 53 (7page)
이용수
초록· 키워드
오류제보하기
Purpose: It appears that much of the discordance between skin prick test (SPT) and ImmunoCAP in clinical practice. We investigated the comparison and correlation between SPT and ImmunoCAP for inhalant allergens.
Methods: A total of 1,400 patients who were tested SPT and ImmunoCAP were recruited from June 2011 to May 2014 in Dong-A University Hospital, and the results of two assays were compared for 17 inhalant allergens. For SPT, mean wheal size≥3 mm or allergen/histamine≥1 at 15 minutes, and the result of ImmunoCAP of ≥0.35 kU/L was considered positive, respectively.
Results: Of the study subjects, bronchial asthma was 29.3%, rhinitis 36.8%, atopic dermatitis 0.6%, and chronic urticaria 4.3%. The agreement rate of between two assays was 77.4%. When ImmunoCAP was compared with SPT as the reference, the sensitivity, specificity was 75.5% and 80.0%, respectively. Significant correlation was observed (r=0.59), and birch, mugwort, Japanese hop, house dust mites, and cockroach showed very strong correlation (r>0.7).
Conclusion: The agreement, sensitivity, and specificity between SPT and ImmunoCAP was various according to allergens. We should determine the clinical relevance of the allergen sensitization using both SPT and ImmunoCAP not alone with combination of clinical symptoms.
목차
등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Axetn R / 1988 / A new laboratory diagnostic system applied to allergy testing / N Engl Reg Allergy Proc 9:503~508
Leimgruber A / 1991 / Clinical evaluation of a new in-vitro assay for specific IgE, the immuno CAP system / Clin Exp Allergy 21:127~131
Bousquet J / 1990 / Comparison between RAST and Pharmacia CAP system : a new automated specific IgE assay / J Allergy Clin Immunol 85:1039~1043
Ollert M / 2005 / Allergen-specific IgE measured by a continuous random-access immunoanalyzer : interassay comparison and agreement with skin testing / Clin Chem 51:1241~1249
Jiang XD / 2011 / Correlation analysis of two serum-specific immunoglobulin E test systems and skin-prick test in allergic rhinitis patients from Northeast China / Am J Rhinol Allergy 25:116~119
Leimgruber A / 1991 / Clinical evaluation of a new in-vitro assay for specific IgE, the immuno CAP system / Clin Exp Allergy 21:127~131
Bousquet J / 1990 / Comparison between RAST and Pharmacia CAP system : a new automated specific IgE assay / J Allergy Clin Immunol 85:1039~1043
Ollert M / 2005 / Allergen-specific IgE measured by a continuous random-access immunoanalyzer : interassay comparison and agreement with skin testing / Clin Chem 51:1241~1249
Jiang XD / 2011 / Correlation analysis of two serum-specific immunoglobulin E test systems and skin-prick test in allergic rhinitis patients from Northeast China / Am J Rhinol Allergy 25:116~119
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