청소년기 비만지표와 초기 성인기 경동맥 내중막 두께와의 관련성: Kangwha Study

이유정; 남정모; 김현창; 허남욱; 서일

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자료유형: 학술저널

저자정보: 이유정 남정모 김현창 허남욱 서일

저널정보: 대한예방의학회 예방의학회지 예방의학회지 제41권 제2호

발행연도: 2008.1

수록면: 107 - 114 (8page)

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Objectives : The aim of this study is to investigate the association between obesity indices (body mass index, weight, waist-hip ratio and waist circumference) in adolescents and the carotid intima-media thickness (C-IMT) in early adulthood. We also wanted to identify the best predictor for C-IMT among these obesity indices. Methods : This study used community-based prospective cohort study, known as the Kangwha Study, and the data we used were from subjects who were 16-years old in 1996 (defined as HadolescenceI) and 25 years-old in 2005 (defined as Hearly adulthoodI). The 256 subjects (113 men and 143 women) who were used for analysis participated in both follow-ups, and they underwent B-mode ultrasonography of the carotid arteries at the early adulthood follow-up. Obesity indices were defined as the body mass index, weight, waist-hip ratio and waist circumference. The C-IMT was defined as the mean of the maximal IMT of each common carotid artery. The C-IMT and obesity indices associations were evaluated via multivariable regression, logistic regression and the receiver-operator characteristic curve analyses. Results : In men, all the obesity indices in adolescence were showed to have statistically significant positive association with C-IMT in early adulthood. However, no such relationship was showed in women. On multiple regression and logistic regression analysis, the waist-hip ratio showed the biggest relationship with the C-IMT among the 4 obesity indices. However, there were no statistical significant differences and no best predictor was found. For the women, the obesity incidences and C-IMT showed no relationships. Conclusions : This study suggested that obesity in adolescence was related to an increase C-IMT in healthy young Korean men.

#Obesity #Carotid artery thrombosis #Adult #Adolescence

참고문헌 (23)

참고문헌 신청

Davis

De Michele, M. / 2002 / Association of obesity and central fat distribution with carotid artery wall thickening in middle-aged women / Stroke 33 (12) : 2923 ~ 2928

Ebbeling, C.A. / 2002 / Childhood obesity: Public-health crisis, common sense cure / Lancet 360 (9331) : 473 ~ 482

Ferreira, I. / 2004 / Current and adolescent body fatness and fat distribution: relationships with carotid intimamedia thickness and large artery stiffness at the age of 36

Freedman, D.S. / 2004 / The relation of obesity throughout life to carotid intimamedia thickness in adulthood: The Bogalusa Heart Study / Int J Obes Relat Metab Disord 28 (1

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