지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제46권 제5호
- 발행연도
- 2016.1
- 수록면
- 350 - 359 (10page)
이용수
초록· 키워드
오류제보하기
Purpose: The purpose of the present study was to evaluate the effectiveness of a minimal concentration of bone morphogenetic protein-2 (BMP-2) in terms of quantitative and qualitative analyses of newly formed bone in a rabbit maxillary sinus model. Methods: In 7 rabbits, sinus windows were prepared bilaterally. Biphasic calcium phosphate (BCP) loaded with 0.05 mg/mL BMP-2 was grafted into one sinus (the BMP group) and saline-soaked BCP was placed into the other (the control group) in each animal. The animals were allowed an 8-week healing period before being sacrificed. Specimens including the augmented area and surrounding tissues were then removed and evaluated both radiographically and histologically. Results: There was a difference in the mineralization of new bone between the groups. In the BMP group, the greater part of the new bone consisted of mature lamellar bone with an evident trabecular pattern, whereas the control group showed mostly woven bone, consisting only partially of lamellar bone. Histometrically, the area of new bone was significantly greater (4.55±1.35 mm2 vs. 2.99±0.86 mm2) in the BMP group than in the control group ( P <0.05); however, the total augmentation volumes were not significantly different between the groups. Conclusions: Within the limitations of this study, it can be suggested that a minimal concentration of BMP-2 (0.05 mg/mL) had an osteoinductive effect with accelerated mineralization in a rabbit sinus model using a BCP carrier.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Kim JS / 2015 / Acceleration of bone regeneration by Bmp-2-loaded collagenated biphasic calcium phosphate in rabbit sinus / Clin Implant Dent Relat Res 17:1103~1113
LeGeros RZ / 2003 / Biphasic calcium phosphate bioceramics: preparation, properties and applications / J Mater Sci Mater Med 14:201~209
Lim HC / 2015 / Effect of different hydroxyapatite:beta-tricalcium phosphate ratios on the osteoconductivity of biphasic calcium phosphate in the rabbit sinus model / Int J Oral Maxillofac Implants 30:65~72
Mangano C / 2015 / A human clinical, histological, histomorphometrical, and radiographical study on biphasic HA-beta-TCP 30/70 in maxillary sinus augmentation / Clin Implant Dent Relat Res 17:610~618
Choi Y / 2013 / Recombinant human bone morphogenetic protein-2 stimulates the osteogenic potential of the Schneiderian membrane: a histometric analysis in rabbits / Tissue Eng Part A 19:1994~2004
LeGeros RZ / 2003 / Biphasic calcium phosphate bioceramics: preparation, properties and applications / J Mater Sci Mater Med 14:201~209
Lim HC / 2015 / Effect of different hydroxyapatite:beta-tricalcium phosphate ratios on the osteoconductivity of biphasic calcium phosphate in the rabbit sinus model / Int J Oral Maxillofac Implants 30:65~72
Mangano C / 2015 / A human clinical, histological, histomorphometrical, and radiographical study on biphasic HA-beta-TCP 30/70 in maxillary sinus augmentation / Clin Implant Dent Relat Res 17:610~618
Choi Y / 2013 / Recombinant human bone morphogenetic protein-2 stimulates the osteogenic potential of the Schneiderian membrane: a histometric analysis in rabbits / Tissue Eng Part A 19:1994~2004
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Sinus augmentation using rhBMP-2-loaded synthetic bone substitute with simultaneous implant placement in rabbits
Journal of Periodontal & Implant Science
2017 .01
-
Comparative study of bone regeneration using fibrin sealant with xenograft in rabbit sinus: pilot study
Maxillofacial Plastic Reconstructive Surgery
2021 .01
-
Biosilicated collagen/β-tricalcium phosphate composites as a BMP-2-delivering bone-graft substitute for accelerated craniofacial bone regeneration
생체재료학회지
2021 .01
-
Stepwise verification of bone regeneration using recombinant human bone morphogenetic protein-2 in rat fibula model
대한구강악안면외과학회지
2017 .01
-
Late-term healing in an augmented sinus with different ratios of biphasic calcium phosphate: a pilot study using a rabbit sinus model
Journal of Periodontal & Implant Science
2016 .01
-
Three-dimensionally printed biphasic calcium phosphate blocks with different pore diameters for regeneration in rabbit calvarial defects
생체재료학회지
2022 .09
-
Effects of micro-porosity and local BMP-2 administration on bioresorption of β-TCP and new bone formation
생체재료학회지
2019 .01
-
Maxillary sinus augmentation using biphasic calcium phosphate: dimensional stability results after 3–6 years
Journal of Periodontal & Implant Science
2019 .01
-
Sinus floor augmentation using a mineralized freeze-dried bone graft combined with recombinant human bone morphogenetic protein-2: clinical and histological results of three cases
Oral Biology Research
2021 .12
-
Effectiveness of biphasic calcium phosphate block bone substitutes processed using a modified extrusion method in rabbit calvarial defects
Journal of Periodontal & Implant Science
2015 .01
-
rhBMP-2를 이용한 상악동거상술의 성공적인 치료 전략
대한치과의사협회지
2015 .01
-
Comparison of immunohistochemical analysis on sinus augmentation using demineralized tooth graft and bovine bone
대한구강악안면외과학회지
2021 .08
-
Lateral approach for maxillary sinus membrane elevation without bone materials in maxillary mucous retention cyst with immediate or delayed implant rehabilitation: case reports
대한구강악안면외과학회지
2017 .08
-
Influence of biodegradable polymer membrane on new bone formation and biodegradation of biphasic bone substitutes: an animal mandibular defect model study
Maxillofacial Plastic Reconstructive Surgery
2020 .01
-
Bone defect model in animals for evaluation of bone grafts
한국실험동물학회 학술발표대회 논문집
2016 .02
-
Review of Computer-Aided Sinus Surgery
Hanyang Medical Reviews
2016 .01
-
Effects of Escherichia Coli-derived Recombinant Human Bone Morphogenetic Protein-2 Loaded Porous Hydroxyaptite-based Ceramics on Calvarial Defect in Rabbits
대한골대사학회지
2017 .01
-
Bioactive calcium phosphate materials and applications in bone regeneration
생체재료학회지
2019 .01
-
Bone formation around rhBMP-2- coated implants in rabbit sinuses with or without absorbable collagen sponge grafting
Journal of Periodontal & Implant Science
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0