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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objectives: This study investigated the effect of SM-2015 on blood alcohol clearance and hangover. We undertook this study to test whether SM-2015 is effective in decreasing blood alcohol concentration and preventing the symptoms of alcohol-induced hangover.
Methods: Twenty healthy volunteers participated in this randomized crossover study. All participants were classified between an SM-2015 intake group (test group) and a non-intake group (control group).
The primary outcome measure was the difference in blood alcohol concentration and hangover severity scores between the test and control groups. The secondary outcome measure was the difference in a liver function test (LFT) between the test and control groups.
Results: After alcohol exposure, the sensitivity scores of blood alcohol concentration and hangover symptoms (sleepiness, dizziness, nausea, weakness, stomach pain, diarrhea, and concentration disorder) were significantly decreased in the SM-2015 intake group compared with the non-intake group. There were no differences in the LFT results between the SM-2015 intake group and the non-intake group.
Conclusions: SM-2015 is effective in decreasing blood alcohol concentration and preventing the symptoms of alcohol-induced hangover. Larger studies are required to confirm these findings.
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등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Cheng N / 2013 / Antioxident and hepatoprotective effects of Schisandra chinensis pollen extract on CCl4induced acute liver damage in mice / Food Chem Toxicol 5 : 234 ~ 240
Cho SH / 2001 / Effect of plant extracts on the activity of alcohol dehydrogenase and the antioxidation in alcohol-treated rat hepatocyte / J Korean Soc Food Sci Nutr 30 : 67
Hikino H / 1984 / Antihepatotoxic actions of lignoids from Schizandra chinensis fruits / Planta Med 50 : 213 ~ 218
Kimura Y / 1982 / Effects of geniposide isolated from Gardenia jasminoides on metabolic alterations in high sugar diet-fed rats / Chem Pharm Bull 30 : 4444 ~ 4447
Kiso Y / 1984 / Antihepatotoxic principles of Artemisia capillaris buds / Planta Med 50 : 81 ~ 85
Cho SH / 2001 / Effect of plant extracts on the activity of alcohol dehydrogenase and the antioxidation in alcohol-treated rat hepatocyte / J Korean Soc Food Sci Nutr 30 : 67
Hikino H / 1984 / Antihepatotoxic actions of lignoids from Schizandra chinensis fruits / Planta Med 50 : 213 ~ 218
Kimura Y / 1982 / Effects of geniposide isolated from Gardenia jasminoides on metabolic alterations in high sugar diet-fed rats / Chem Pharm Bull 30 : 4444 ~ 4447
Kiso Y / 1984 / Antihepatotoxic principles of Artemisia capillaris buds / Planta Med 50 : 81 ~ 85
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