지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 39 - 49 (11page)
이용수
초록· 키워드
오류제보하기
Objective : Phyllostachyos Folium (PF) has been used to treat patients with febrile disease consuming the body fluids marked by fever with restlessness, thirst etc. In the theory of herbology, PF can clear away heat and promote the production of the body fluids, relieve restlessness. Recently PF is known to have anti-bacterial, anti-oxidantic effects.
Methods : The present study was carried out to investigate the effects of PF on solid tumor in mice in terms of immune-potentiating and direct cytotoxic action of PF in vitro and vivo study. The present author investigated thymocyte and splenocyte proliferation to confirm immune-potentiating activity of PF and also investigated tumor/body weight ratio and survival rates in tumor bearing mice.
Result : In this study, administration of PF decreased tumor/body weight ratio significantly, and prolonged survival duration compared to non-treated control. In addition, treatment with PF suppressed proliferation rate of Sarcoma 180 (S-180) cells significantly, and elevated proliferation rates of thymocytes isolated from normal mice. These results were co-related with in vivo study.
Conclusion : In conclusion, these results suggest that PF is useful to treat patient with solid tumor, because PF has direct toxic action for tumor cell and immune -potentiating action for T cells. Further study will need to elucidate exact mechanisms related in anti-cancer action of PF.
목차
등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
/ / 2007년 사망 및 사망원인 통계결과
Dwyer JM / 1981 / use of concanavalin A to study the immunoregulation of human T cells / Clin Exp Immunol 46 (2) : 237 ~ 249
Fidler, I. J / 1987 / Review biologic heterogeneity og cancer metastasi / Brest Cancer Res
Hyung Woo Kim / 2007 / Therapeutic Efficacy of Extracts from Root of Acnthopanax Sessiliflorus as Anti-cancer Drug ; in vivo and in vitro Study / 동의생리병리학회지 21 (2) :
Kriukova IN / 1983 / Expression of Thy 1 thymocyte differentiation antigen in mouse mammary cancer cells in vitro / Biull Eksp Biol Med 96 (8) : 81 ~ 84
Dwyer JM / 1981 / use of concanavalin A to study the immunoregulation of human T cells / Clin Exp Immunol 46 (2) : 237 ~ 249
Fidler, I. J / 1987 / Review biologic heterogeneity og cancer metastasi / Brest Cancer Res
Hyung Woo Kim / 2007 / Therapeutic Efficacy of Extracts from Root of Acnthopanax Sessiliflorus as Anti-cancer Drug ; in vivo and in vitro Study / 동의생리병리학회지 21 (2) :
Kriukova IN / 1983 / Expression of Thy 1 thymocyte differentiation antigen in mouse mammary cancer cells in vitro / Biull Eksp Biol Med 96 (8) : 81 ~ 84
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