지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Inflammatory markers have been shown to play an important role in bone remodeling. The purpose of this study was to investigate the relationship among serum C-reactive protein (CRP), adiponectin, tumor necrosis factor-alpha (TNF-α) and bone health in healthy adults. Methods: We measured serum levels of CRP, adiponectin, TNF-α as well as lumbar spine and femoral neck bone mineral density (BMD) in 76 adults. Anthropometric measurements and nutrient intake survey of participants were carried out.
The participants were divided into two groups (normal BMD group=40; 52.6%, decreased BMD group=36; 47.4%). Results: The CRP concentration was significantly higher in the decreased BMD group. The adiponectin concentration was lower in the decreased BMD group but the difference was not significant. The TNF-α concentration was higher in the decreased BMD group, the difference was not significant. The participants in the decreas ed BMD group were found to have lower calcium intakes. The sodium intake of the decreased BMD group was significantly higher. The BMD in the decreased BMD group show ed inverse correlations with CRP and dietary sodium intake. Conclusions: Serum CRP and dietary sodium intake is associated with BMD. Further research is needed to confirm the potential role of inflammatory marker to modulate the effects on bone.
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참고문헌 (21)
참고문헌 신청
Korean Society for Bone and Mineral Research / Physician’s guide for diagnosis & treatment of osteoporosis
Firooznia H / 1984 / Quantitative computed tomography assessment of spinal trabecular bone. I. Age-related regression in normal men and women / J Comput Tomogr 8:91~97
Matkovic V / 1992 / Calcium intake and peak bone mass / N Engl J Med 327:119~120
Labouesse MA / 2014 / Associations among endocrine, inflammatory, and bone markers, body composition and weight loss induced bone loss / Bone 64:138~146
Koroglu BK / 2011 / Relation of leptin, adiponectin and insulin resistance to bone mineral density in type 2 diabetic postmenopausal women / Endokrynol Pol 62:429~435
Firooznia H / 1984 / Quantitative computed tomography assessment of spinal trabecular bone. I. Age-related regression in normal men and women / J Comput Tomogr 8:91~97
Matkovic V / 1992 / Calcium intake and peak bone mass / N Engl J Med 327:119~120
Labouesse MA / 2014 / Associations among endocrine, inflammatory, and bone markers, body composition and weight loss induced bone loss / Bone 64:138~146
Koroglu BK / 2011 / Relation of leptin, adiponectin and insulin resistance to bone mineral density in type 2 diabetic postmenopausal women / Endokrynol Pol 62:429~435
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