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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 130 - 134 (5page)
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초록· 키워드
오류제보하기
Apoptosis, the cel's intrinsic death program, plays a crucial role in the regulation of tisue ho-meostasis, and abnormal inhibition of apoptosis is an indicator of cancer and autoimune diseases, whereas excessive cell death is implicated in neu-ease (AD). Using cDNA subtraction analysis, we compared p60TRP (p60 transcription regulator pro-tein) expresing cels with control cels during the process of apoptosis and we identified the new zinc-finger protein p48ZnF that is predominantly located in the cytoplasm of the cell. Aditionally, we demonstrate here that p48ZnF is up-regulated in rat neuronal PC12 cells upon stimulation with the neurotrophic factor NGF (50 ng/ml). These in the control of neuronal survival.
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참고문헌 (12)
참고문헌 신청
/ 1997 / Anew generation of protein database search programs : 3389 ~ 402
/ 1997 / Better prediction of protein cellularlocalization sites with the k nearest neighbor classifier : 147 ~ 52
/ 1999 / 1313 multiple alignments match themajority of proteins : 260 ~ 3 62
/ 2000 / Induction of rat L-phosphoserinephosphatase by amyloid-beta : 1 37 ~ 42 11 40
/ 2000 / Regulation of neuronal cell death and differentiationby NGF and IAP family members : 247 ~ 59
/ 1997 / Better prediction of protein cellularlocalization sites with the k nearest neighbor classifier : 147 ~ 52
/ 1999 / 1313 multiple alignments match themajority of proteins : 260 ~ 3 62
/ 2000 / Induction of rat L-phosphoserinephosphatase by amyloid-beta : 1 37 ~ 42 11 40
/ 2000 / Regulation of neuronal cell death and differentiationby NGF and IAP family members : 247 ~ 59
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