지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.1
- 수록면
- 668 - 676 (9page)
이용수
초록· 키워드
오류제보하기
Stem cells are used for the investigation of developmental processes at both cellular and organism levels and offer tremendous potentials for clinical applications as an unlimited source for transplantation. Gangliosides, sialic acid-conjuga - ted glycosphingolipids, play important regulatory roles in cell proliferation and differentiation. How - ever, their expression patterns in stem cells and during neuronal differentiation are not known. Here, we investigated expression of gangliosides during the growth of mouse embryonic stem cells (mESCs), mesenchymal stem cells (MSCs) and differentiated neuronal cells by using high-performance thin-layer chromatography (HPTLC). Monosialoganglioside 1 (GM1) was expressed in mESCs and MSCs, while GM3 and GD3 were expressed in embryonic bodies.
In the 9-day old differentiated neuronal cells from mESCs cells and MSCs, GM1 and GT1b were exp - ressed. Results from immunostaining were consis - tent with those observed by HPTLC assay. These suggest that gangliosides are specifically expressed according to differentiation of mESCs and MSCs into neuronal cells and expressional difference of ga - ngliosides may be a useful marker to identify differentiation of mESCs and MSCs into neuronal cells.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
/ / an acidic membrane component that increase during macro-phage-like cell differentiation can induce monocytic differ-entiation of human myeloid and monocytoid leulcemic c
/ 1981 / Establishment in culture of pluri-potent cells from mouse embryos 292 : 154 ~ 6
/ 1981 / Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cell 78 : 7634 ~ 8
/ 1984 / Distribution of the ganglioside GD3 in human nervous sys-tem detected by R24 mouse monoclonal antibody 324 : 190 ~ 4
/ 1985 / Correlation between ganglioside distribution and histological grading of human astrocytomas 36 : 363 ~ 6
/ 1981 / Establishment in culture of pluri-potent cells from mouse embryos 292 : 154 ~ 6
/ 1981 / Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cell 78 : 7634 ~ 8
/ 1984 / Distribution of the ganglioside GD3 in human nervous sys-tem detected by R24 mouse monoclonal antibody 324 : 190 ~ 4
/ 1985 / Correlation between ganglioside distribution and histological grading of human astrocytomas 36 : 363 ~ 6
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Roles of gangliosides in mouse embryogenesis and embryonic stem cell differentiation
Experimental and Molecular Medicine
2011 .01
-
The roles of glycosphingolipids in the proliferation and neural differentiation of mouse embryonic stem cells
Experimental and Molecular Medicine
2009 .01
-
Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model
Experimental and Molecular Medicine
2008 .01
-
Differentiation of human gingival mesenchymal stem cells into neuronal lineages in 3D bioconjugated injectable protein hydrogel construct for the management of neuronal disorder
Experimental and Molecular Medicine
2016 .01
-
Transcriptional Profiling in Neuronal Differentiation of Stem Cells
한국유전체학회 Conference
2003 .01
-
Ganglioside GM3 is involved in neuronal cell death
한국당과학회 학술대회
2006 .01
-
Nuclear receptor regulation of stemness and stem cell differentiation
Experimental and Molecular Medicine
2009 .01
-
Mass spectrometry based proteomic analysis of human stemcells: a brief review
Experimental and Molecular Medicine
2007 .01
-
Differentiation of mesenchymal stem cells on nanopillar/pit array structures
한국진공학회 학술발표회초록집
2017 .02
-
Significance of Glycosphingolipds as a Differential Maker during Neuronal Differentiation of Mouse Embryonic Stem Cells.
한국당과학회 학술대회
2006 .01
-
PKC-δ inhibitors sustain self-renewal of mouse embryonic stem cells under hypoxia in vitro
Experimental and Molecular Medicine
2010 .01
-
Statistical Analysis about Ability to Mouse Embryonic Stem Cell Differentiation using cDNA Microarray
한국데이터정보과학회지
2005 .12
-
Overexpression of bone morphogenetic protein 4 in STO fibroblast feeder cells represses the proliferation of mouse embryonic stem cells in vitro
Experimental and Molecular Medicine
2012 .01
-
Functional Classification of Gene Expression Profiles During Differentiation of Mouse Embryonic Cells on Monolayer Culture
Animal cells and systems
2009 .01
-
The RUNX1 Enhancer Element eR1: A Versatile Marker for Adult Stem Cells
Molecules and Cells
2020 .01
-
The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation
Experimental and Molecular Medicine
2013 .01
-
Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10
Experimental and Molecular Medicine
2009 .01
-
Stem cell therapy for Alzheimer’s disease and related disorders: current status and future perspectives
Experimental and Molecular Medicine
2015 .01
-
A Survey of Genes Expressed in Undifferentiated Mouse Embryonic Stem Cells to Isolate and Characterize New Developmental/Differentiation - Specific Regulatory Genes
한국동물학회 학술대회
1996 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0