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논문 기본 정보
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- 학술저널
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- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제19권 제11호
- 발행연도
- 2009.1
- 수록면
- 1,333 - 1,341 (9page)
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Haematococcus pluvialis, a green alga, accumulates astaxanthin
(3,3'-dihydroxy-β,β'-carotene-4,4'-dione) upto 2-3% on a
dry weight basis. In the present study, identification of
carotenoids from Haematococcus cyst cell extract by HPLC
and LC-MS (APCI) and their antioxidant properties were
evaluated in in vitro model systems. The extract exhibited
89% and 78% antioxidant activities in the β-carotene
linoleate model and the hydroxyl radical scavenging model,
at 9 ppm of total carotenoid, respectively. The extract also
showed 80%, 85%, and 79% antioxidant activities against
lipid peroxidation in the kidney, brain, and liver of rats.
Low-density lipoprotein oxidation induced by Cu2+ ions
was also protected (45%, 64%, and 75%) by the extract in
a dose-dependent manner with different carotenoid levels.
Thiobarbituric acid reactive substances concentration in
the blood, liver, and kidney of rats were also significantly
(p<0.005) decreased in H. pluvialis-treated rats. The potent
antioxidant activity is attributable to various carotenoids
present in the extract.
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참고문헌 (25)
참고문헌 신청
Aboul-Enein, A. M. / 2003 / Antioxidant activity of algal extracts on lipid peroxidation / J. Med. Sci 3 : 87 ~ 98
Ben Amortz, A. / 1996 / Bioavailability of natural isomers mixture compared with synthetic all-trans β-carotene in human serum / Am. J. Clin. Nutr 63 : 729 ~ 734
Ceron, M. C. / 2007 / Antioxidant activity of Haematococcus pluvialis cells grown in continuous culture as a function of their carotenoid and fatty acid content / Appl. Micro
Chidambaramurthy, K. N. / 2005 / In vivo antioxidant activity of carotenoids from Dunaliella salina - a green micro alga / Life Sci 76 : 1381 ~ 1390
Davies, B. H. / 1976 / Carotenoids. in: Chemistry and Biochemistry of Plant Pigments / Academic Press : 38 ~ 166
Ben Amortz, A. / 1996 / Bioavailability of natural isomers mixture compared with synthetic all-trans β-carotene in human serum / Am. J. Clin. Nutr 63 : 729 ~ 734
Ceron, M. C. / 2007 / Antioxidant activity of Haematococcus pluvialis cells grown in continuous culture as a function of their carotenoid and fatty acid content / Appl. Micro
Chidambaramurthy, K. N. / 2005 / In vivo antioxidant activity of carotenoids from Dunaliella salina - a green micro alga / Life Sci 76 : 1381 ~ 1390
Davies, B. H. / 1976 / Carotenoids. in: Chemistry and Biochemistry of Plant Pigments / Academic Press : 38 ~ 166
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