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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 250 - 254 (5page)
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초록· 키워드
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Introduction: This study evaluated the bone regenerative effect of silk fibroin mixed with platelet-rich fibrin (PRF) of a bone defect in rabbits.
Materials and Methods: Ten New Zealand white rabbits were used for this study and bilateral round shaped defects were formed in the parietal bone (diameter: 8.0 mm). The silk fibroin mixed with PRF was grafted into the right parietal bone (experimental group). The left side (control group)was grafted only PRF. The animals were sacrificed at 4 weeks and 8 weeks. A micro-computerized tomography (μCT) of each specimen was taken.
Subsequently, the specimens were decalcified and stained for histological analysis.
Results: The average value of plane film analysis was higher in the experimental group than in the control group at 4 weeks and 8weeks after surgery. However, the difference was not statistically significant.(P>0.05) The tissue mineral density (TMD) in the experimental group at 4 weeks after surgery was significantly higher than the control group.(P<0.05)Conclusion: Silk fibroin can be used as a scaffold of PRF for rabbit calvarial defect repair.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Altman GH / 2003 / Silk-based biomaterials / Biomaterials 24 : 401 ~ 416
Bhanot S / 2002 / Current applications of platelet gels in facial plastic surgery / Facial Plast Surg 18 : 27 ~ 33
Buser D / 1999 / Localized ridge augmentation with autografts and barrier membranes / Periodontol 2000 19 : 151 ~ 163
Cao Y / 2009 / Biodegradation of silk biomaterials / Int J Mol Sci 10 : 1514 ~ 1524
Carlson ER / 1995 / The potential for HIV transmission through allogeneic bone. A review of risk and safety / Oral Surg Oral Med Oral Pathol Oral Radiol Endod 80 : 17 ~ 23
Bhanot S / 2002 / Current applications of platelet gels in facial plastic surgery / Facial Plast Surg 18 : 27 ~ 33
Buser D / 1999 / Localized ridge augmentation with autografts and barrier membranes / Periodontol 2000 19 : 151 ~ 163
Cao Y / 2009 / Biodegradation of silk biomaterials / Int J Mol Sci 10 : 1514 ~ 1524
Carlson ER / 1995 / The potential for HIV transmission through allogeneic bone. A review of risk and safety / Oral Surg Oral Med Oral Pathol Oral Radiol Endod 80 : 17 ~ 23
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