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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.1
- 수록면
- 352 - 359 (8page)
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MMP-2 and MMP-9, type IV collagenases which degrade basement membrane, have been known to play important roles in invasion and metastasis of tumor cells, In addition, they seem to be involved in cell differentiation, apoptosis, angiogenesis and immunity, etc. We immunohistochemically examined epithelial and stromal expressions of MMP-2 and MMP-9 in irritation fibroma, oral leukoplakia, and oral squamous cell carcinoma (OSCC) and have some results as follows:
1. Irritation fibromas, oral leukoplakias and OSCCs mostly showed increased expression of MMP-2 and MMP-9 in the epithelium and connective tissue compared with normal mucosa.
2. There was a significant difference in the epithelial expression of MMP-2 and MMP-9 between irritation fibroma and oral leukoplakia.
3. There was a significant difference in the epithelial and stromal expression of MMP-2 and MMP-9 between irritation fibroma and OSCC.
4. There was a significant difference in the stromal expression of MMP-9 between oral leukoplakia and OSCC.
We concluded that rritation fibroma, oral leukoplakia and OSCC have somewhat different characteristics of MMP-2 and MMP-9 expressions, which perhaps result from different pathogenesis.
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등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
/ 1995 / Oral and Maxillifacial Pathology
/ 1995 / Oral epithelial dysplasia and the development of invasive squamous cell carcinoma 79 : 321 ~ 329
/ 1996 / Complex roles of matrix metalloproteinases in tumor progression Attempts to Understand Metastasis Formation I : 1 ~ 21
/ 1996 / Expressino of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response 149 (1) : 273 ~ 282
/ 1996 / Matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase (MMP-9) type IV collagenases in colorectal cancer 56 (1) : 190 ~ 196
/ 1995 / Oral epithelial dysplasia and the development of invasive squamous cell carcinoma 79 : 321 ~ 329
/ 1996 / Complex roles of matrix metalloproteinases in tumor progression Attempts to Understand Metastasis Formation I : 1 ~ 21
/ 1996 / Expressino of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response 149 (1) : 273 ~ 282
/ 1996 / Matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase (MMP-9) type IV collagenases in colorectal cancer 56 (1) : 190 ~ 196
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