지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 255 - 261 (7page)
이용수
초록· 키워드
오류제보하기
Background: Through differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation.
Keratinocyte differentiation is disturbed in several skin diseases such as psoriasis and atopic dermatitis. Objective:The aim of this study is to evaluate the keratinocyte differentiation-enhancing effect of rose absolute oil (RAO).
Methods: Primary cultured human normal keratinocytes were treated with RAO, and differentiation then checked by the expression of marker genes. Results: RAO did not induce cytotoxicity on cultured keratinocytes at a dose of 10μM.
The level of involucrin, an early marker for keratinocyte differentiation, was significantly increased by RAO. Concomitantly,RAO increased involucrin promoter activity,indicating that RAO increased involucrin gene expression at the mRNA level. Furthermore, RAO increased the level of filaggrin in cultured keratinocytes, and in the granular layer of mouse skin. In line with these results, RAO decreased the proliferation of keratinocytes cultured in vitro. When RAO was applied topically on the tape-stripped mouse skins, it accelerated the recovery of disturbed barrier function.
Conclusion: These results suggest that RAO may be applicable for the control of skin texture and keratinocyte differentiation-related skin diseases.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Blumenberg M / 1997 / Human epidermal keratinocyte:keratinization processes / EXS 78 : 1 ~ 29
Chandar P / 2009 / Understanding natural moisturizing mechanisms: implications for moisturizer technology / Cutis (1 Suppl) : 2 ~ 15
Chu DH / 2008 / Development and structure of skin. In: Fitzpatrick's dermatology in general medicine. 7th ed / McGraw-Hill : 57 ~ 73
Contet-Audonneau JL / 1999 / A histological study of human wrinkle structures:comparison between sun-exposed areas of the face,with or without wrinkles,and sun-protected are
Elias PM / 2005 / Stratum corneum defensive functions:an integrated view / J Invest Dermatol 125 : 183 ~ 200
Chandar P / 2009 / Understanding natural moisturizing mechanisms: implications for moisturizer technology / Cutis (1 Suppl) : 2 ~ 15
Chu DH / 2008 / Development and structure of skin. In: Fitzpatrick's dermatology in general medicine. 7th ed / McGraw-Hill : 57 ~ 73
Contet-Audonneau JL / 1999 / A histological study of human wrinkle structures:comparison between sun-exposed areas of the face,with or without wrinkles,and sun-protected are
Elias PM / 2005 / Stratum corneum defensive functions:an integrated view / J Invest Dermatol 125 : 183 ~ 200
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Single Low-Dose Radiation Induced Regulation of Keratinocyte Differentiation in Calcium-Induced HaCaT Cells
Annals of Dermatology
2016 .01
-
The Role of Nkx2.5 in Keratinocyte Differentiation
Annals of Dermatology
2009 .01
-
RAO를 이용한 고관절증(염)의 5가지 치료 모델
Hip and Pelvis
2012 .01
-
Role of Keratinocytes in the Development of Vitiligo
Annals of Dermatology
2012 .01
-
Epigenetic Modulation of Gene Expression during Keratinocyte Differentiation
Annals of Dermatology
2012 .01
-
Kinetin Improves Barrier Function of the Skin by Modulating Keratinocyte Differentiation Markers
Annals of Dermatology
2017 .01
-
Immortalization of Primary Keratinocytes and Its Application to Skin Research
Biomolecules & Therapeutics(구 응용약물학회지)
2015 .01
-
Calcium-induced Human Keratinocytes (HaCaT) Differentiation Requires Protein Kinase B Activation in Phosphatidylinositol 3-Kinase-dependent Manner
Toxicological Research
2006 .09
-
녹차의 피부보호효과
대한화장품학회지
2005 .01
-
배양된 구강점막 각화상피세포가 누드마우스 피부 창상 치유에 미치는 효과
대한구강악안면외과학회지
2004 .01
-
Chitosan Increases α6 Integrin/CD71 Human Keratinocyte Transit-Amplifying Cell Population
Biomolecules & Therapeutics(구 응용약물학회지)
2010 .01
-
Engineering of a Human Skin Equivalent
대한화장품학회지
2003 .01
-
Inhibition of Poly(I:C)-Induced Inflammation by Salvianolic Acid A in Skin Keratinocytes
Annals of Dermatology
2019 .01
-
IL-1 Receptor Antagonist Reduced Chemical-Induced Keratinocyte Apoptosis through Antagonism to IL-1α/IL-1β
Biomolecules & Therapeutics(구 응용약물학회지)
2018 .01
-
Comparison of Gene Expression Profiles between Keratinocytes, Melanocytes and Fibroblasts
Annals of Dermatology
2013 .01
-
Ampelopsis japonica Makino Extract Inhibits the Inflammatory Reaction Induced by Pathogen-Associated Molecular Patterns in Epidermal Keratinocytes
Annals of Dermatology
2016 .01
-
Establishment of Immortalized Primary Human Foreskin Keratinocytes and Their Application to Toxicity Assessment and Three Dimensional Skin Culture Construction
Biomolecules & Therapeutics(구 응용약물학회지)
2017 .01
-
Induction of Interleukin-22 (IL-22) production in CD4+ T Cells by IL-17A Secreted from CpG-Stimulated Keratinocytes
Annals of Dermatology
2016 .01
-
Protection of the Flowers of Prunus persica Extract from Ultraviolet B-Induced Damage of Normal Human Keratinocytes
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2000 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0