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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.10
- 수록면
- 353 - 359 (7page)
이용수
초록· 키워드
오류제보하기
The purpose of this study was to investigate the effect of 7-MEGA™ 500 on the improvement of skin aging in an UVB-induced photo-aging model of hairless mice. The dorsal skin of hairless mice was exposed to UVB three times a week for 12 weeks to induce skin wrinkle. After inducing the wrinkle, 7-MEGA™ 500 was orally administered once a day for 4 weeks. Skin thickness, skin barrier function, and wrinkle indicators were improved by treatment with 7-MEGA™ 500. Both gene and protein expression levels of MMP-3 and c-Jun in skin were significantly decreased by 7-MEGA™ 500. Therefore, the intake of 7-MEGA™ 500 is thought to have a positive effect on the improvement of skin aging, although further studies are needed.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (23)
참고문헌 신청
Kim, H. H. / 2006 / Photoprotective and anti-skinaging effects of eicosapentaenoic acid in human skin in vivo / J. Lipid Res 47:921~930
Kim, H. H. / 2005 / Augmentation of UV-induced skin wrinkling by infrared irradiation in hairless mice / Mech. Ageing Dev 126:1170~1177
Storey, A. / 2005 / Eicosapentaenoic acid and docosahexaenoic acid reduce UVB- and TNF-alpha-induced IL-8 secretion in keratinocytes and UVB-induced IL-8 in fibroblasts / J. Invest. Dermatol 124:248~255
Wol Soon Jo / 2012 / Effect of Microalgal Extracts of Tetraselmis suecica against UVB-Induced Photoaging in Human Skin Fibroblasts / 한국독성학회지 28(4):241~248
Otton, R. / 2012 / Combined fish oil and astaxanthin supplementation modulates rat lymphocyte function / Eur. J. Nutr 51:707~718
Kim, H. H. / 2005 / Augmentation of UV-induced skin wrinkling by infrared irradiation in hairless mice / Mech. Ageing Dev 126:1170~1177
Storey, A. / 2005 / Eicosapentaenoic acid and docosahexaenoic acid reduce UVB- and TNF-alpha-induced IL-8 secretion in keratinocytes and UVB-induced IL-8 in fibroblasts / J. Invest. Dermatol 124:248~255
Wol Soon Jo / 2012 / Effect of Microalgal Extracts of Tetraselmis suecica against UVB-Induced Photoaging in Human Skin Fibroblasts / 한국독성학회지 28(4):241~248
Otton, R. / 2012 / Combined fish oil and astaxanthin supplementation modulates rat lymphocyte function / Eur. J. Nutr 51:707~718
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